4c), that is, to the time of the transition-related activity in the LH (Fig. 1f). During the out-of-phase LH–LPO stimulation, the phase signatures of the three behaviors were uncoordinated, lacking the typical for behavioral transitions increase of their magnitude near oscillation peaks (...
1a,c), and Dm3 is a strong output of Tm1 (Extended Data Fig. 2d). Figure 1e shows a typical Dm3 cell receiving strong Tm1 input in three collinear columns, even though the cell extends over many columns (Fig. 1b–d). The Tm1 cells presynaptic to each Dm3v cell were mapped to ...
4c), that is, to the time of the transition-related activity in the LH (Fig. 1f). During the out-of-phase LH–LPO stimulation, the phase signatures of the three behaviors were uncoordinated, lacking the typical for behavioral transitions increase of their magnitude near oscillation peaks (...
9,10 Together, this suggests a mechanism whereby the neural circuit we have described preferentially elicits male-typical mating displays in males. BNSTprTac1 neurons of sexually naive males provide a neuronal activity signature of sex recognition, a signature predictive of subsequent mating with ...
Means Calmodulin: a prototypical calcium sensor Trends Cell Biol., 10 (8) (2000), pp. 322-328, 10.1016/s0962-8924(00)01800-6 View PDFView articleView in ScopusGoogle Scholar [54] R. Grabski, J. Dewit, J. De Braekeleer, M. Malicka-Blaskiewicz, P. De Baetselier, H. Verschueren ...
Pathologic TDP-43 accumulation is one of the typical pathophysiological manifestations in ALS. Tamoxifen has been validated to enhance autophagy through the mTOR-dependent pathway by inhibiting AKT/PKB and increase the clearance of TDP-43 aggregates. A small phase II clinical trial initiated to explor...
Differential expression status (difference in the proportion of real zeros), DE abundance (typical DE without proportion of zeros change), DE general (both DE and proportion of zeros change). The majority of information is in supplementary material. Paper Miao, Zhun, Ke Deng, Xiaowo Wang, ...
For primary (de novo) GBMs, which account for 80% of all GBMs, the median age of diagnosis is 62114. Secondary GBMs, which develop from lower-grade astrocytomas or oligodendrogliomas, are more frequent in younger adults (mean age 45 years)114,115. The typical treatment course for ...
(1)) on the response behavior of the AdEx model of a typical SC neuron (nr 100), the time dependence of the neuron’s membrane potential, V(t), is shown in Fig. 5, when the input (applied at T = 15 deg) varied in population size, σpop (Fig. 5a), or in stimulus ...
Members of the Slit family share a typical conserved domain structure. They contain an N-terminal signal peptide targeting them for secretion, four leucine-rich repeats mediating receptor interaction, seven (Drosophila) to nine (vertebrates) glutamic acid–glycine-phenylalanine (EGF) repeats, a lamin...