FEN1 is able to adopt conformations in which it can swing out from PCNA via a hinge region, and it has been proposed that this could allow for a tracking mode for the complex, as well as for a “locked down” mode that is catalytically functional. In addition, it was noted that ...
These interactions limit the swing of loop 2, and further affect the interactions of the substrate and other functional amino acids. The OE2 of Glu175 shows a dis- tance of approximately 2.9 Å to the side chain N atom of Lys135, which permits the formation of salt and hydro- gen ...
[38]. They also reported that the dynamic stability of the supporting leg contributes to the swing velocity of the kicking leg [38]. Chew-Bullock et al. (2014) clarified that the single leg balance ability in the supporting leg affects kicking accuracy in the kicking leg [40]. These ...
Athletes capable of producing high horizontal ground reaction force also display high eccentric torque production by the hip extensors (especially hamstrings) at the end of the swing phase of the stride cylce [2]. At the same time, it has been reasoned that athletes are most susceptible to ...
SMYD5 belongs to a special class of protein lysine methyltransferases with an MYND (Myeloid-Nervy-DEAF1) domain inserted into a SET (Suppressor of variegation, Enhancer of Zeste, Trithorax) domain. Despite recent advances in its functional characterizati