Here we test the hypothesis that aripiprazole (ARIP), an atypical APD with partial D 2 and 5-HT 1A receptor agonist activities will improve recovery after TBI and when combined with EE will further enhance the benefits. Anesthetized adult male rats received either a controlled cortical impact ...
This was based on a study that found that augmentation of venlafaxine with aripiprazole improved treatment outcomes in treatment-resistant patients.46 It was also chosen due to its dual mechanism of action (at low versus high doses). Participants were included if they were 465 years of age, ...
Fig. 5. Electrophiles target distinct functional protein systems in protein alkylation susceptibility classes. GO biological groups at right were based on shared proteins and functional similarity (GO biological processes significantly enriched for Class I, II, and III protein targets are listed in supp...
This was based on a study that found that augmentation of venlafaxine with aripiprazole improved treatment outcomes in treatment-resistant patients.46 It was also chosen due to its dual mechanism of action (at low versus high doses). Participants were included if they were >65 years of age, ...
Cortical lesion volume was smaller in all treated groups compared to the TBI + STD + VEH group (p < 0.05). The data replicate previous work and extend the findings by demonstrating that 1) ARIP promotes recovery after TBI, but combining treatments does not yield additional benefits, which ...
To assess the effect of the long-acting antipsychotic aripiprazole lauroxil (AL) on social and functional outcomes compared with placebo in patients with acute schizophrenia, a post-hoc analysis was conducted. Patients with acute schizophrenia were enrolled in a 12-week, double-blind, placebo-...
Our approach does a reasonably good job of distinguishing patients from controls, and the distinction is sharper for patients and controls who have been treated with Aripiprazole. Unexpectedly, we find that this increased separation between patients and controls is associated with a change in the ...
The most potent drug was olanzapine, followed by risperidone, aripiprazole, and amisulpride. All drugs showed significant differences between groups. Conclusion: Our pilot study demonstrated that antipsychotics impair visual cortical function. This finding underscores the importance of monitoring for visual ...