Aripiprazole: A drug with a novel mechanism of action and possible efficacy for alcohol depend- ence. CNS Neurol Disord Drug Targets. 9(1): 50-54.Vergne DE, Anton RF (2010) Aripiprazole: a drug with a novel mecha- nism of action and possible efficacy for alcohol dependence. CNS Neurol ...
Patients who do not respond to or tolerate one drug may be successfully treated with an agent from a different class or with a different adverse effect profile.Immediate-release aripiprazole injection (no longer commercially available in the US) has been used IM for acute management of agitation ...
Drug Class:Antipsychotics, Second Generation, Antimanic Agents What is aripiprazole, and what is it used for? Aripiprazole is an atypical antipsychotic medication used to treatschizophrenia,bipolar disorderand related psychiatric conditions in adults and children. Aripiprazole is a second-generation antipsyc...
Dosage adjustments are recommended in patients who are known CYP2D6 poor metabolizers and in patients taking concomitant CYP3A4 inhibitors or CYP2D6 inhibitors or strong CYP3A4 inducers (see Table 2). When the co-administered drug is withdrawn from the combination therapy, ABILIFY dosage should th...
For example, the new drug product might combine two previously approved active ingredients, or be a new dosage form, or use a new drug delivery mechanism. An organization may want to develop a new drug that uses well-known active ingredients from an approved product and target a new ...
Aripiprazole (Abilify). The newest, longactingaripiprazole (an arylpiperazine quinolinone derivative),appears to be partial agonist of D2receptors (i.e., itstimulates certain D2 receptors while blocking others dependingon their locations in the brain and the concentrationof drug). Bioavailability of...
Significant weight gain reported with therapy; monitor waist circumference and BMI Drug interaction overview See Dosage Modifications Strong CYP3A4 and CYP2D6 inhibitors: Coadministration of oral aripiprazole with strong CYP3A4 or CYP2D6 inhibitors increased the exposure of aripiprazole compared to the us...
Abilify, also known by its generic name aripiprazole, is an antipsychotic medication that belongs to a class of drugs called atypical antipsychotics. It works by affecting the activity of certain chemicals in the brain, specifically dopamine and serotonin, which helps to restore the balance of neuro...
AbilifyMaintena (aripiprazole) is anantipsychoticdrug used for the treatment ofschizophrenia. What Are Side Effects of Abilify Maintena? The most common side effect of Abilify Maintena is a movement disorder characterized by a feeling of inner restlessness and a compelling need to be in constant mot...
The drug increased DNA damage in blood, but did not show mutagenic effects, suggesting that it might affect long-term genomic stability. Keywords: antipsychotic agent; aripiprazole; locomotion; memory; genotoxic/mutagenic activities; DNA damage; lipoperoxidation Acta Pharmacologica Sinica (2011) 32: ...