Aripiprazole is one of the most recently introduced neuroleptics and offers a particular mode of action: apart from its D2 antagonistic activity, it is also a partial D2 and 5-HT1-A receptor agonist and a 5-HT2-A antagonist (Croxtall, 2012). Over the past decade, it has become the ...
receptors and antagonist activity at 5-HT2A receptors, with a low side-effect profile.Areas covered: This descriptive review gives a short overview of the pathology and epidemiology of AD, including psychotic symptoms, and describes the mode of action of aripiprazole and results of preclinical ...
A brief summary of some neuroprotective medicinal herbs and their mode of action is discussed in the following section. Show moreView chapterExplore book Next Generation Therapeutics Jeffrey J Rakofsky, ... Charles B Nemeroff, in Current Opinion in Chemical Biology, 2009 Atypical antipsychotics (...
Aripiprazole is a new atypical antipsychotic with a mode of action that is distinct from currently available antipsychotic drugs. In phase III comparative ... D Naber,M Lambert - Progress in Neuro-Psychopharmacology and Biological Psychiatry 被引量: 186发表: 2004年 DEUTERIUM-ENRICHED ARIPIPRAZOLE The...
Aripiprazole is a new atypical antipsychotic with a mode of action that is distinct from currently available antipsychotic drugs. In phase III comparative ... D Naber,M Lambert - Progress in Neuro-Psychopharmacology and Biological Psychiatry 被引量: 186发表: 2004年 DEUTERIUM-ENRICHED ARIPIPRAZOLE The...
Aripiprazole is a new atypical antipsychotic with a mode of action that is distinct from currently available antipsychotic drugs. In phase III comparative clinical studies, aripiprazole 15–30 mg/day was at least as effective as haloperidol and risperidone in short term treatment of acute exacerbation...
The injected mass was 0.75±0.33 mg, specific activity was 1378±964 Ci/mmol, and activity dose was 2.39±1.38 mCi at time of injection (n ¼ 28). PET Scanning Positron emission tomography (PET) imaging was per- formed in 3D mode with the high-resolution ECAT EXACT HR + scanner (...
Aripiprazole is a new atypical antipsychotic with a mode of action that is distinct from currently available antipsychotic drugs. In phase III comparative ... D Naber,M Lambert - Progress in Neuro-Psychopharmacology and Biological Psychiatry 被引量: 187发表: 2004年 ...
Aripiprazole is a new atypical antipsychotic with a mode of action that is distinct from currently available antipsychotic drugs. In phase III comparative ... D Naber,M Lambert - Progress in Neuro-Psychopharmacology and Biological Psychiatry 被引量: 187发表: 2004年 ...
Results: Among Week 2 MADRS Responders, the median and mode CGI-S scores at Week 2 were 2 (borderline mentally ill) for both adjunctive aripiprazole (n ¼ 88) and adjunctive placebo (n ¼ 42), while the median and mode CGI-S scores among Week 2 adjunctive aripiprazole (n ¼ 299)...