RNA Polymerase IIProtein ConformationTranscription, GeneticModels, MolecularStructure-Activity RelationshipThis chapter discusses the structure and function of RNA polymerase II. High-resolution structural studies of polymerase II (Pol II) by x-ray crystallography required large amounts of pure protein that...
The σ factor σ 70 of E. coli RNA polymerase acts not only in initiation, but also at an early stage of elongation to induce a transcription pause, and simultaneously to allow the phage λ gene Q transcription antiterminator to act. We identify the signal in DNA that induces early pausing...
Learn about the process of transcription inside a cell with a focus on the structure and function of the RNA polymerase ii in the process.
Many nuclear and cytoplasmic condensates are rich in RNA and RNA-binding proteins (RBPs), which undergo liquid–liquid phase separation (LLPS). Whereas the role of RBPs in condensates has been well studied, less attention has been paid to the contribution of RNA to LLPS. In this Review, ...
Structure and membrane topography of the Vibrio-type secretin complex from the type 2 secretion system of enteropathogenic Escherichia coli. J. Bacteriol. 200, e00521-17 (2018). Google Scholar Fei, J. & Sharma, C. M. RNA localization in bacteria. Microbiol. Spectr. https://doi.org/...
The influenza virus-associated RNA polymerase cleaves capped RNA in an endonucleolytic manner and the transcription is initiated by the addition of GMP, the first substrate to be polymerized under the direction of viral RNA template, onto 3'-termini of resulting capped RNA fragments. In the prese...
All cis-acting frameshift signals encoded in mRNAs are minimally composed of two functional elements: a heptanucleotide “slippery sequence” conforming to the general form X XXY YYZ, followed by an RNA structural element, usually an H-type RNA pseudoknot, positioned an optimal number of ...
Analysis of RNAi mutants of plastid-targeted phage-type RNA polymerase in Arabidopsis Virus entry into cells is a complex, multistep process that requires the coordinated activities of a large number of cellular factors and multiple membrane... Kabeya,Y,Sugita,... - 《Plant & Cell Physiology》...
et al. Tyrosine phosphorylation of RNA polymerase II CTD is associated with antisense promoter transcription and active enhancers in mammalian cells. eLife 3, e02105 (2014). Article PubMed PubMed Central Google Scholar Hsin, J. P., Li, W., Hoque, M., Tian, B. & Manley, J. L. RNA...
et al. A protein complex required for polymerase V transcripts and RNA- directed DNA methylation in Arabidopsis. Curr. Biol. 20, 951–956 (2010). Article PubMed Central CAS PubMed Google Scholar Zhong, X. H. et al. DDR complex facilitates global association of RNA polymerase V to ...