Kim KH, Seong BL (2003) Pro-apoptotic function of HBV X protein is mediated by interaction with c-FLIP and enhancement of death-inducing signal. EMBO J 22:2104–2116Kim KH,Seong HL.Pro-apoptotic function of HBV X protein is mediated by interaction with C-FLIP and enhancement of death -...
Liver function tests, or LFTs, include tests for bilirubin, a breakdown product of hemoglobin, and ammonia, a protein byproduct that is normally converted into urea by the liver before being excreted by the kidneys. LFTs also commonly include tests to measure levels of several enzymes, which ar...
The HBV HBx gene encodes a small regulatory protein that is essential for viral replication and is suspected to play a role in viral pathogenesis. HBx stimulates cytoplasmic signal transduction pathways, moderately stimulates a number of ... F Su,CN Theodosis,RJ Schneider - 《Journal of Virology...
Hepatitis B virus (HBV) X protein (HBx) has been determined to play a crucial role in the replication and transcription of HBV, and its biological functions mainly depend on the interaction with other host proteins. This study aims at screening the proteins that bind to the key functional dom...
To examine the effect of HBV expression, cells were cultured in the absence of tetracycline. To avoid potential confounding effects of tetracycline on cell metabolism, standard HepG2 cells were used as negative controls. Expression of viral protein in the majority of cells was confirmed for each ...
The hepatitis B virus (HBV) particles bear a receptor-binding site located in the pre-S1 domain of the large HBV envelope protein. Using the hepatitis delta virus (HDV) as a surrogate of HBV, a second infectivity determinant was recently identified in the envelope proteins antigenic loop (AGL...
Hepatitis B virus (HBV) X protein (pX) is implicated in hepatocellular carcinoma (HCC) pathogenesis by an unknown mechanism. Deletions or mutations of gene... WH Wang,RL Hullinger,OM Andrisani - 《Journal of Biological Chemistry》 被引量: 181发表: 2008年 Hepatitis B virus X mutants, present...
After analyzing the HBV genome by a computer program, a p53 response element binding sequence was found in HBV genome at upstream of enhancer I, from 1047 to 1059 nucleotides. This sequence could specifically bind to p53 protein, increase p53 protein accumulation in the PHC cells and stimulate ...
indirect measurement of core protein of Hep B virus hepatitis B core antibody antibody to Hep B core antigen -develops before HBsAb in acute infection HBeAg e antigen of HBV is a degradation product of pre-HBcAg -present in acute infection ...
371 \\{HAPS\\} \\{HEPATITIS\\} B \\{VIRUS\\} (HBV) \\{CAPSID\\} \\{INHIBITORS\\} \\{AFFECT\\} \\{CORE\\} \\{PROTEIN\\} \\{INTERACTION\\} \\{WITH\\} \\{THE\... A series of novel Heteroaryldihydropyrimidines (HAPs) derivatives were designed and synthesized as potent in...