Thus Il-1 was produced in such mouse astrocyte cultures after stimulation with lipopolysaccharide (LPS) or spontaneously by rat astrocytes and by rat and human glioblastoma cells. The glioblastoma cell derived Il-1 like factor has been shown to be neutralized by an antiserum against human ...
By using connexin-30-knockout mice, this study found that connexin-30, an astrocyte protein known for its role in gap junctions, is also involved in PAP ensheathment of synapses. Increased synaptic ensheathment is associated with reduced synaptic strength and LTP expression in the hippocampus. ...
using a cell-specific CRISPR–Cas9 approach, we demonstrate thatfgfr3andfgfr4are required for vertebrate astrocyte morphogenesis. This work provides the first visualization of astrocyte morphogenesis from stem cell to post-mitotic astrocyte in vivo, identifies a role for Fgf receptors in vertebrate ast...
Regulatory role of astrocyte-expressed fatty acid binding protein 7 (FABP7) on morphology and synaptic plasticity of cortical neurons Fatty add binding proteins (FABPs) are key regulators of lipid metabolism, energy homeostasis, and inflammation. They participate in fatty acid metabolism ... Majid,...
Astrocyte culture models: Molecular and function characterization of primary culture, immortalized astrocytes and C6 glioma cells The understanding of the physiology of astrocytes and their role in brain function progresses continuously. Primary astrocyte culture is an alternative met... Galland, FabianaSead...
Thus, we recognize histamine as an important player in the modulation of astrocytic functions that deserves further considerations in exploring involvement of astrocytes in neurological disorders. 展开 关键词: Histamine Histamine receptors Astrocyte function ...
Connexin43 is involved in the effect of endothelin-1 on astrocyte proliferation and glucose uptake. In previous studies, we showed that endothelin-1 increased astrocyte proliferation and glucose uptake. These effects were similar to those observed with ot... S Herrero-González,JC Valle-Casuso,R ...
rotenone may depend upon proper astrocytic mitochondrial functioning, we hypothesized that DJ-1 deficiency would impair astrocyte mitochondrial motility, fission/fusion dynamics, membrane potential maintenance, and respiration, both at baseline and as an enhancement of rotenone-induced mitochondrial dysfunction...
Calcium-dependent activation of Erk-1 and Erk-2 after hypo-osmotic astrocyte swelling. The influence of hypo-osmotic cell swelling on the activity of the mitogen-activated protein (MAP) kinases Erk-1 and Erk-2 (where Erk stands for extracellu... F Schliess,R Sinning,R Fischer,... - 《...
Effects of Methamphetamine Self-Administration and Extinction on Astrocyte Structure and Function in the Nucleus Accumbens Coredoi:10.1016/j.neuroscience.2019.03.040B. SiemsenC. ReichelK. LeongC. Garcia‐KellerC. GipsonS. SpencerJ. McFaddin