The most common type of dementia is the Alzheimer’s disease (AD) [1], which is neuropathologically characterized by accumulated amyloid-β (Aβ) peptide protein and intraneuronal tangles of hyperphosphorylated micro tubule-associated protein tau [2]. The number of dementia patients has been ...
Exogenous lipids require the involvement of transport molecules, including CD36, fatty acid transport protein family (FATPs/SLC27), and fatty acid-binding proteins (FABPs) [4]. Notably, recent studies have established a link between the overexpression of these transport molecules and the poor ...
Mechanism and therapeutic targets of neurodegenerative disorders The presence of protein aggregates, oxidative stress, and inflammation within CNS marks neurodegenerative disorders. Various biological progressions have been allied to these disorders, including neurotransmitter depletion or insufficient synthesis, ab...
The majority of natural products in EOs are hydrophobic, making them more likely to penetrate and disrupt the cell membranes of bacteria [34]. Membrane disruption leads to loss of pH gradient, the collapse of protein pumps, drainage of the adenosine triphosphate (ATP) pool, loss of cellular co...
In children, dietary protein intake is necessary to replenish protein turnover and to meet growth needs. The daily protein requirement from 4 to 7 years is 0.86 g/kg (PRI) and rises to 0.92 g/kg in the pre-pubertal phase [1, 28]. The adolescent’s higher protein requirement ...
the protein that is formed in type 2 diabetes is thesame proteinwhich is responsible for causing Alzheimer’s disease! High levels of insulin swamp certain enzyme so that it stops breaking down amyloid which accumulates in the brain leading to Alzheimer’s!Prof. Edward McNay a researcher at ...
Protein expression was normalized to that of β-actin in the same sample. The relative band intensities were quantified using Image Lab Version 2.0.1 (Bio-Rad). Enzyme-linked immunosorbent assays (ELISAs) for cytokine determination The levels of serum cytokines IL-1β, IL-6, TNF-α and IL...
Table 4 Effects of dietary Acremonium terricola culture treatment on egg quality of Beijing You-chickens (n = 60) Full size table Nutritional ingredients of yolk The effects of ATC on nutritional ingredient contents in the yolk of eggs are shown in Table 5. The contents of protein and le...
Finally, the amount of protein in the supernatant and the primary solution was measured using the Bradford assay [38]. The UV-visible absorbance of the encapsulated and non-encapsulated samples was determined. Moisture content Moisture content was determined according to the method described by ...
Moreover, garlic chives-derived nanovesicles have shown the ability to inhibit the activation of the NOD-like receptor family pyrin domain-containing protein 3 (NLRP3) inflammasome, with 1,2-diacyl-sn-glycerol-3-phosphate (DLPC) as the primary active substance [41]. These research findings ...