with a headcount poverty ratio of less than $1.25 per day. While the global economy has been slowly recovering from the pandemics, recent political tensions have sparked a higher inflationary episode. Consequently, food prices have risen, and the supply of essential items such as wheat, barley, ...
Hypernym discovery entails identifying all possible instances of hypernyms for a given query within the vocabulary [8]. Recently, hypernym discovery studies have used word embeddings to capture the meaning and relationship between words. These studies can be further categorized into two classes: word2v...
1). Once inclusion and exclusion criteria are broadly met (pre-screening), interested persons are invited to partake in an information/dialogue meeting (group/individually) to understand eligibility and the meaning of participating in the trial more fully, before signing their written consent (30–...
isolated from an AKR mouse T cell lymphoma [1], was found to carry transduced sequences of cellular origin [1]. Our collaborative work with Philip Tsichlis and Stephen Staal led to cloning the viral oncogene v-aktas the oncogene transduced by the AKT8 retrovirus (originally...
Functional meaning of mutationsPersonalized therapyMutation searchMutation functional classesDespite its apparently simple genetics,cystic fibrosis(CF)is a rather complex genetic disease.A lot of variability in the steps of the path from the cystic fibrosis transmembrane conductance regulator(CFTR)gene to ...
Heterophilic graphs refer to graphs where linked nodes exhibit heterophily, meaning that they have dissimilar features and different class labels [29]. Many real-world graphs, such as transaction networks [45], exhibit heterophily. Recent studies have shown that GNNs do not perform well on hete...
A combination of multiple types of transcription factors and cis-regulatory elements is often required for gene expression in eukaryotes, and the combinatorial regulation confers specific gene expression to tissues or environments. To reveal the combinatorial regulation, computational methods are developed th...
Xnas the multivariate endpoint of a Brownian motion on the phylogeny. The initial value of the process is the unknown parameterμat the root, which we will henceforth callXAto reflect its meaning as the unobserved ancestral datum. We begin this section by exploiting the reversibility of the ...
A large trial with a narrow CI around the difference between the active control and the new treatment might show that the lower limit of the interval lies within the margin, meaning that the new treatment is non-inferior to the active control, but the upper limit of the interval is below ...
However, the exact meaning of the terms activation and inhibition is not clear, especially when several interactions combine on a gene: Does an activation of b by a forbid an inhibition of b by a or not? Is an activation of b by a necessarily observed all along the border associated to ...