We compared the healthcare experiences and health outcomes of cisgender autistic (n = 1094), transgender/gender diverse autistic (n = 174), and cisgender non-autistic adults (n = 1295) via an anonymous, self-report survey. All individuals whose sex assigned at birth did not m...
Some argue that if we accept that trans identification is non-pathological, it does not require exploration, just as there is generally no need to explore the psychological formation of cisgender identities. It has been pointed out that this argument does not hold, as it is based on a ...
Enhancers are key cis-acting elements that regulate the spatiotemporal expression of genes [1]. Enhancers are linear distal noncoding regions that stimulate transcription via long-range cis-chromatin interactions independent of their genomic orientation. In addition to typical enhancers (TEs), the genom...
Furthermore, computational approaches to solve "splicing codes" (e.g [3, 4]) are mainly focused on genome-wide prediction of cis-regulatory elements. Validation of results and inferences from these approaches still requires slow and expensive low-throughput approaches. Another limitation of current ...
Functional meaning of mutationsPersonalized therapyMutation searchMutation functional classesDespite its apparently simple genetics,cystic fibrosis(CF)is a rather complex genetic disease.A lot of variability in the steps of the path from the cystic fibrosis transmembrane conductance regulator(CFTR)gene to ...
it is worth noting that when sex assigned at birth was referred, the terms "male" and "female" are used. When referring to gender identity, the terms "man", "women" and "gender diverse" are used. However, for the sake of clarity, the terms "cisgender man" and "cisgender woman" ha...
A large trial with a narrow CI around the difference between the active control and the new treatment might show that the lower limit of the interval lies within the margin, meaning that the new treatment is non-inferior to the active control, but the upper limit of the interval is below ...
The robustness of the conclusion was determined by assessing the consistency of the results of the NMA effect size (SMDs and 95% CIs) and SUCRA probabilities before and after conducting sensitivity analyses. Publication bias and grade of evidence We used a comparison-adjusted funnel plot and Egger...
The intrinsic frequency has the meaning of wave frequency in the reference frame moving with the local wind. For definiteness, we assume thatm > 0 whenm2 > 0 and Imm > 0 whenm2 < 0. In upward- and downward-propagating waves, vertical displacement of fluid particles is ...
The layers' meaning is: /h1H,(H4,6,7,8,9,10,11) atom number 1 has one H, 4 atoms H are shared by atoms 6,7,8,9,10, and 11 /f/h8,10H,6H2 atom 6 has 2H, atom 8 has 1H, atom 10 has 1H. Table 2Tautomerism patterns detected by InChI ...