Hairpin probe is a new type of fluorescent-labeled nucleic acid probe with a hairpin structure, which has high sensitivity and specificity (Fig. 3I). In the free state, the fluorophore and the quenching group are close to each other, which quenches the fluorescence. When hybridizing with the...
Interest in Human Action Recognition (HAR), which encompasses both household and industrial settings, is growing. HAR describes a computer system’s capacity to accurately recognize and evaluate human activities and behaviors, akin to what humans call pe
Moreover, the human body’s self-repair ability is very limited; therefore, regulating and invoking gene therapy is a very promising method to further improve the therapeutic effect. Gene therapy is the introduction of genes into cells to up-regulate the expression of target genes to treat or ...
Adipose-derived stem cells (ADSCs) have been extensively used in preclinical and clinical trials for treating various diseases. However, the differences between ADSCs from lean individuals (L-ADSCs) and those from obese individuals (O-ADSCs) have not bee
When she died last year, her cabinet was still full of jars—carefully labeled with a mysterious system of letters and numbers. For example “08P” might mean plum jam cooked in 2008. On some jars, the writing faded and only after carefully removing the tight lid would we be able to te...
The presence of labeled GFP-NOVA2–RNA complexes was dependent on both UV crosslinking and the expression from the Chat:GFP-Nova2 transgene, further demonstrating the specificity of GFP-NOVA2 CLIP under these conditions (Fig. 2a, lanes 1–3). Partially digested RNA crosslinked to GFP-NOVA2 ...
(adapted from Zhao et al. [35]).aMultiple views of the sharpened map of the trimeric channel with the major domains labeled, with the three subunits colored red, green and blue.bCartoon model in which the three subunits are colored red, green and blue. In the middle panel, the front ...
Octocorals are one of the most ubiquitous benthic organisms in marine ecosystems from the shallow tropics to the Antarctic deep sea, providing habitat for numerous organisms as well as ecosystem services for humans. In contrast to the holobionts of reef-
A funny thing happened with the launch of ChatGPT:much of theAIthat had been deployed up until then got labeled overnight as “Traditional AI”, in contrast to “Generative AI”. This was a little bit of a shock to many AI practitioners and companies that up until then were considered ...
A labeled phylogeny has the advantage of allowing sophisticated hypothesis testing. An obvious application of the inferred history of the tree is detection of clearly discordant sequences from which we may suspect an intrusion or defect of some sort. In particular, an abnormally high number of bran...