Because total-body (TB) PET systems with long axial fields-of-view have many lines-of-response, there is a need for fast MC programs that model relevant aspects of PET imaging for optimizing data acquisition and/or estimating scatter and spurious coincidences. We developed a fast MC (fMC) ...
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We labeled calnexin, an ER marker, in monocytes from both HDs and patients with GD and calculated the median fluorescence intensity (MFI). Our findings revealed a significantly higher expression of calnexin in monocytes from GD patients (P = 0.004; Fig. 3A, B) hence confirming ER ...
Hairpin probe is a new type of fluorescent-labeled nucleic acid probe with a hairpin structure, which has high sensitivity and specificity (Fig. 3I). In the free state, the fluorophore and the quenching group are close to each other, which quenches the fluorescence. When hybridizing with the...
Then, the cells were incubated with the primary antibody (anti-CRT or anti-HMGB1, 1:200) at 4 ℃ overnight and incubated with the fluorescent-labeled secondary antibody (1:200) at room temperature for 2 h. Finally, the fluorescence images were taken with an inverted fluorescence microscope ...
BM can occur in various types of cancers and significantly reduces the quality of life of patients by causing skeleton-related events leading to serious immobility [40]. CRPC is an advanced form of PCa that develops due to disease progression following surgical or chemical castration, and approxim...
To generate StaVia’s cartographicAtlas View, we first create a single-cell embedding infused with second-order LTRW features learned from the TI cluster graph (see “Methods”). Specifically, based on the presence of sequential data (e.g. data labeled with different time points), the single...
There are two hypotheses of the origin of larval skeletogenesis; the first posits a single origin of adult skeletogenesis followed by multiple origins of larval skeletogenesis and convergent evolution of larval skeleton. This is owing to the phylogenetic placement of ophiuroids (which produce larval sk...
The black arrows indicate the fluorescently labeled A549 cells. B The number of A549 HERC5 KO cells compared to parental cells per zebrafish embryo is significantly increased in the whole body as well as separately in the brain and the body at 3 days post injection (whole body: p = ...
Roles of mechanosensitive channel Piezo1/2 proteins in skeleton and other tissues. Bone Res. 2021;9(1):44. Article CAS PubMed PubMed Central Google Scholar Bosshardt DD, Chappuis V, Buser D. Osseointegration of titanium, titanium alloy and zirconia dental implants: current knowledge and open...