The good interpretability of SPACE in representing spatial domains, combined with this consistency, forms the foundation for its superior performance. SpaDo enables multi-slice spatial domain detection We illustrated the utility of SpaDo to detect spatial domains that can be comparable across multiple ...
Possible mechanisms of ATP-dependent chromatin remodelers in the regulation of plant immunity during fungal infection. SYD (Splayed protein) and BRM (Brahma protein) are recruited to target loci and regulate the expression of defense-related genes. BRM also promotes the nucleosome stability. PIE1 (...
This article focuses on the innovative forms and variants of these technologies. Imaging-based ST strategies Image-based ST technologies include fluorescence in situ hybridization (ISH)- and in situ sequencing (ISS)-based methods. The advent of high-resolution microscopy and single-molecule ...
Plant somatic cell regeneration includes organogenesis and somatic embryogenesis pathways, which represent forms of fertilization-independent development. Plant somatic embryogenesis is a process in which somatic cells of a variety of tissues are cultured in vitro to undergo de-differentiation and then re-...
fibroproliferative process due to tension, which inhibits the phosphatidylinositol-3-kinase (PI3K)/Akt pathway associated apoptosis [20]. Thus, a detrimental cycle forms within wounded skin where the mechanical force derived from myofibroblasts in turn activate more fibroblasts in a manner of positive ...
[69]. APOBEC1 was first identified through the discovery of a C-to-U modification in apolipoprotein B (ApoB) mRNA, which results in the expression of two distinct forms of the protein (a truncated form and a full-length form) [71,72]. The full-length ApoB protein is responsible for ...
[256,257,258]. The collection of a saliva sample can be achieved using some forms of environmental enrichment (for example toys), as has been done in pigs using cotton ropes to measure miRNAs in saliva for viral detection at a herd level [259] and chewable silicone sticks to measure ...
Early blight and brown leaf spot are often cited as the most problematic pathogens of tomato in many agricultural regions. Their causal agents are Alternaria spp., a genus of Ascomycota containing numerous necrotrophic pathogens. Breeding programs have y
these systems can be categorized into two forms: those that encapsulate the drug in a reservoir within the polymer coating (reservoir type) and those that embed the drug into the polymer matrix (monolithic type). Drugs can also be carried in a polymer-drug conjugate manner, and targeting facto...
A–C panels show the three forms of structural variation (SV) breakpoint clusters based on different transcripts of TMPRSS2 and ERG, shown in the top right. The number of samples with breakpoint in different exon positions of TMPRSS2-ERG fusion junction is shown in brackets Full size image...