Ferroptosis is a distinct form of programmed cell death characterized by excessive production and accumulation of reactive oxygen species (ROS) and increased lipid peroxidation driven by iron overload [6, 7]. Glutathione peroxidase 4 (GPX4), a key regulator of ferroptosis, suppresses lipid peroxidatio...
Ferroptosis is a newly identified iron-dependent form of death that is becoming increasingly recognized as a promising avenue for cancer therapy. N6-methyladenosine (m6A) is the most abundant reversible methylation modification in mRNA contributing to tumorigenesis. However, the crucial role of m6A modi...
One study demonstrated that the implantation of SDF-1-loaded membranes into periodontal defects in rats enhanced bone formation, hypothesizing through the increased migrative and regenerative ability of PDLSCs [86]. Similarly, another animal model using SDF-1 showed significantly increased PDL length ...
(2018) proposed to design a distortion function based on vertex normals and embeds bit information into bit planes of vertex coordinates. Jang et al. (2018) proposed to use the shape diameter function (SDF) to divide a 3D mesh into several segments. Then the watermark is embedded into all...
Over the past decade, chimeric antigen receptor (CAR)-T cell therapy has emerged as a revolutionary immunotherapeutic approach to combat cancer. This therapy constructs a CAR on the surface of T cells through genetic engineering techniques. The CAR is fo
Amante C, Neagu M, Falcone G, Russo P, Aquino RP, Nicolais L, et al. Hyaluronate loaded advanced wound dressing in form ofin situforming hydrogel powders: Formulation, characterization, and therapeutic potential. Int J Biol Macromol. 2024;274:133192. ...
Photo crosslinking promotes the crosslinking of gelatin and methacryloyl anhydride under UV irradiation to form GelMA, resulting in the controlling the release or localization of therapeutic genes/growth factors, and improving gene therapy accuracy. Gelatin hydrogels exhibit good cell adhesion, ...
= System.Xml.Schema.XmlSchemaForm.Unqualified)] #endif public string TaxInvoiceNumber { get { return fTaxInvoiceNumber; } set { fTaxInvoiceNumber = value; } } } public class RatingValueHandler : Dapper.SqlMapper.TypeHandler<RatingValue> { private...
[39]. The WT PmraZ_G4_3 and mutant PmraZ_∆G4_3d were simulated without or with NMM. The K+ion was placed at the center of the G-tracts to stabilize the G4 structure. The structure of G4 drug NMM was obtained from PubChem (CID 656404) [40] in SDF format and converted to...
We observed that RAW264.7 cells leave long RFs during migration, and migrasomes form on the tip or branching point of the RFs through transmission electron microscopy analysis (Fig. 1). Fig. 1 Migrasomes from RAW264.7 cells. Transmission electron microscopy image of migrasomes after 24 h of ...