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through his letters. These letters form the basis of the text of the songs, where father and daughter “meet” and communicate for the first time. The first movement Vigil, depicts the arrival of the daughter who hopes for a spiritual connection with her father. The second movement describes...
The structure of CAR has been constantly updated (Fig.1). First-generation CAR consisted of an extracellular structural domain recognizing antigen and a single intracellular motif. Still, there were no costimulatory molecules in the structure, making it difficult for CAR-T cells to persist in patie...
by treating unspliced intronic as a form of alternative splicing, BRIE2 allows us to quantify differential transcriptional kinetics between cell types, thus providing us with an efficient way to select biologically relevant features for RNA-velocity analyses. We show on a number of examples that thi...
On this basis, another transcription inhibitor was knocked out to form a double transcription factor knockout strain. The effects of single transcription inhibitor knockout and double knockout strains on protein expression were compared. Results and discussion Directed evolution of strains showing ...
Paolillo C, Spallino I, Gruppo di Autoformazione Metodologica (GrAM). Can C-reactive protein and white blood cell count alone rule out an urgent condition in acute abdominal pain? Intern Emerg Med. 2016;11(1):141–2. Article PubMed Google Scholar Emile SH. Predictive factors for intestin...
Gravity plays an important role in most life forms on Earth. Yet, a complete molecular understanding of sensing and responding to gravity is lacking. While there are anatomical differences among animals, there is a remarkable conservation across phylogen
Realistic meso‐ and macro‐pore structures were reconstructed and combined to form specific bidisperse porous washcoat layers. The study shows that species effective diffusivities vary significantly but not in the same proportion for different structures. For structures featuring poor transport ...
(MEC), expanded our understanding of CAF heterogeneity. Cell–cell interaction analysis conducted within the spatial context highlighted the pivotal roles of matrix CAFs (mCAFs) in tumor angiogenesis and inflammatory CAFs (iCAFs) in shaping the immunosuppressive microenvironment. In patients with breast...
Therefore, same-read molecular haplotyping gains power with sequencing read length, and the major source of error is the sequencing error rate. Although often overlooked because of its simplicity, sequencing is the most common form of molecular haplotyping. Other forms of molecular haplotyping include...