It reduces Aβ deposition in the brain of Aβ-transgenic mice [12,13,14,15]. The reduction in both Aβ deposition and neuroinflammation may synergistically contribute to the improvement of cognitive function observed in multiple non-clinical models. Although the above-proposed mechanism of action ...
OSE cells from aged mice (> 18 months equivalent to > 55 years old women) were enzymatically separated and used to study stem cells. Viable (7-AAD negative) VSELs in the size range of 2–6 µm with a surface phenotype of Lin−CD45−Sca-1+ were enumerated by flow cytometr...
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To investigate the effects of age-associated microbiota composition on inflammaging and its impact on the gut, brain, and retina, we used young (3 months), old (18 months), and aged (24 months) mice. We compared mice receiving microbiota from a different age group (heterochronic) fecal micr...
The tumor growth was suppressed, and the life span of tumor-bearing mice was also prolonged. Therefore, this approach will direct a ferroptosis/apoptosis hybrid anti-cancer therapy [9]. Conversely, ferroptotic agents such as artesunate and erastin can induce the unfolded protein response (UPR) ...
Furthermore, deletion of Shox2 also leads to hypoplasia in the TMJ of mice. In our study, SHOX2 was specially expressed in MSCs of human embryonic TMJC. These results suggest that SHOX2 plays an important role in the function and early differentiation of the MSCs in human embryonic TMJC....
A pentavalent involving five chromosomes will form during meiosis of male black muntjacs, whereas such structures are absent in female black muntjac. (b) Inversion on the neo-Y chromosome revealed by fluorescence in situ hybridization using two Indian muntjac bacterial artificial chromosome (BAC) ...
Matthieu Tachon has been promoting the traditional art form of Tai Chi in his French community for a long time. An orthopaedist by day, Matthieu started his practice in the late fall of 2015 right after his first visit to the birth place of Tai Chi in Chenjiagou, China. World record ...
PDL protects against LPS-induced respiratory inflammation in mice [11]. Upper respiratory symptoms, fever, and altered taste remained the most common presenting symptoms. Extrapulmonary complications are also common, including the gastrointestinal tract, which explains the frequent use of Huoxiangzhengqi ...
In vivo experiments have also demonstrated that orally administered mixtures of PDNVs could restore the physiological condition of mice treated with hydrogen peroxide (H2O2) for 2 weeks, indicating their potent antioxidant capacity and the presence of various bioactive substances, including hydrogen ...