Hemoparasites, like malaria and schistosomes, are constantly faced with the challenges of storing and detoxifying large quantities of heme, released from their catabolism of host erythrocytes. Heme is an essential prosthetic group that forms the reactive
2]. The disease can occur when pathogenic organisms such as fungi, bacteria, and nematodes; soil PH; temperature extremes; changes in the quantity of moisture and humidity in the air; and other elements continuously harm a plant. Plant diseases...
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Decision of number of clusters Figure 2 shows the relationship between number of clusters and values of nRSS indices, nRSS(e) and nRSS(v), calculated with the estimation dataset and the validation dataset, respectively (see Systems and Methods). The value of nRSS decreased as the number of cl...
Hematophagy arose independently multiple times during metazoan evolution, with several lineages of vampire animals particularly diversified in invertebrates. However, the biochemistry of hematophagy has been studied in a few species of direct medical int
Currently, 463 million people are living with diabetes worldwide [1], and recent predictions estimate that the number of affected people may increase to 578 million by the year 2030 [2]. Type 2 diabetes (T2D) is the predominant form of the disease and results from complex interactions between...
Saccharopolyspora spinosa is an important producer of antibiotic spinosad with clarified biosynthesis pathway but its complex regulation networks associated with primary metabolism and secondary metabolites production almost have never been concerned or
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Biomarkers are an integral part of cancer management due to their use in risk assessment, screening, differential diagnosis, prognosis, prediction of response to treatment, and monitoring progress of disease. Recently, with the advent of Chimeric Antigen
The EPC cell line was genetically engineered to overexpress a monomeric, cytosolic form of EGFP (mEGFP) and the nuclear nCas9n using the same method used to develop the CHSE-EC cell line [44]. Briefly, the EPC cell line was engineered using the plasmid pcDNA3.1-Hyg-nCas9n (Addgene #21...