Traditional Chinese medicine polysaccharides (TCMPs) are plentiful and renewable resources with properties such as biocompatibility, hydrophilicity, biodegradability, and low cytotoxicity. Because the polysaccharide molecular chain contains a variety of
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GO and KEGG enrichment analysis were also performed [35], and the results were presented in the form of bubble charts. Molecular docking Molecular docking can be used to evaluate the tightness of binding between the active ingredient and the core target. Molecular docking was performed after ...
Coupled transcription and translation processes in bacteria cause indiscriminate translation of intact and truncated messenger RNAs, inevitably generating nonfunctional polypeptides. Here, we devised a synthetic protein quality control (ProQC) system that enables translation only when both ends of mRNAs are...
5-Aminolevulinic acid (ALA) recently received much attention due to its potential application in many fields such as medicine, nutrition and agriculture. Metabolic engineering is an efficient strategy to improve microbial production of 5-ALA. In this stu
Plant cellulose synthase is one of important glycosyltransferases, which catalytic synthesis a paracrystalline form of H-bonded-β-1, 4-Glc chains. In this study, a unigene that was highly homologous to the Zea Mays cellulose synthase 3(Ces3) sequence was isolated from the sugarcane(Saccharum of...
In fact, the main problems related to the use of E. coli as cellular factory are i) the loss of carbon in the form of acetate during aerobic growth at high growth rates, ii) the inhibition of cellular growth and protein production by acetate [2] and iii) the need for cofactor ...
Scutellaria, a sub-cosmopolitan genus, stands as one of the Lamiaceae family’s largest genera, encompassing approximately 500 species found in both temperate and tropical montane regions. Recognized for its significant medicinal properties, this genus h
present in human milk and they are made up of five basic units including one acid monosaccharide, namely sialic acid (Sia) or N-acetylneuraminic acid; one amino sugar which is known as GlcNAc; three monosaccharides which are l-fucose (Fuc), d-galactose (Gal), and d-glucose (Glc) [28...
EIICBGlc, that is the membranstanding transport protein) and finally to the substrate. Since all components of the PTS, depending on their phosphorylation status, can interact with various key regulator proteins the output of the PTS is represented by the degree of phosphorylation of the proteins ...