Critical appraisal of each included article is attached in Additional file 1: Appendix 4. Data extraction, charting, and analysis A preliminary data extraction form was developed based on the research questions and piloted with 10 included articles by two independent reviewers (MJ and XY). After ...
In blood and urine, [68Ga]Ga-PSMA-Tz existed mainly in the form of the parent compound at 60 min p.i. (Additional file 1: Figure S13). The excellent stability both in vitro and in vivo provided prerequisites to realize the click-mediated pre-targeted in vivo. [68Ga]Ga-PSMA-Tz ...
In an ecosystem, different species/populations interact with each other to form complicated networks through various types of interactions such as predation, competition and mutualism. On the basis of ecological interactions, ecological networks can be grouped as antagonistic, competitive and mutualistic ne...
1). In their simplest form, deletions and inversions were found to be the most common SV types, while consistent with other PCa studies, we observed a low frequency of insertion events (Additional file 1: Fig. S2). Only 15 tumours (8.3%) presented with at least one insertion, which may...
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Wild plants of Vitis closely related to the cultivated grapevine (V. v. vinifera) are believed to have been first domesticated 10,000 years BC around the Caspian Sea. V. v. vinifera is hermaphrodite whereas V. v. sylvestris is a dioecious species. Male f
The biological effects observed in the aforementioned PDNVs form the basis for their tissue protection and repair properties. However, some studies have only conducted a superficial assessment of the PDNVs' activity without delving into the specific underlying mechanisms. It remains unknown whether the...
(Additional file1: Figure S16–19). It is challenging to synthesize ultra-long transcripts using current full-length cDNA synthesis protocols. For example, the central domain ofAHNAKconsists of a tandem 128 aa repeats that is absent in its ultra-long form in PacBio data, whereas the short...
Whenever a loop starts, the class iterates through the nested hierarchy of objects by following keys that match the current state (idle, talking), body form (M, F), current view (full, upper, mid, head), and/or probabilities (alt + p). The next animation will be created internally ...
Guanine-rich sequences are able to form complex RNA structures termed RNA G-quadruplexes in vitro. Because of their high stability, RNA G-quadruplexes are proposed to exist in vivo and are suggested to be associated with important biological relevance. However, there is a lack of direct eviden...