Renal cell carcinoma (RCC), one of the ten most common cancers, occurs in both sporadic and inherited forms. MiT family translocation RCC, is an aggressive form of the disease [1,2,3] which accounts for 1–5% of sporadic RCC and represents 42% of kidney cancer in children and young adu...
Design of targeted drug delivery systems based on biomaterials and nanomaterials is one of the most feasible strategies to solve the aforementioned problems. Targeted drug delivery systems can effectively improve the solubility and in vivo drug distribution of poorly soluble drugs; nanoparticles are passiv...
The fractalkine is a sole ligand that couples to CX3CR1, existing in either membrane-anchored or soluble form. The membrane-anchored FKN (mFKN), soluble FKN (sFKN), and CX3CR1 were analyzed by immunoblotting (Fig. 2a). After 4 weeks of fructose feeding, the sFKN was increased in...
All the data processes of MINI are the same as BENCH except for removing the pairs showing pair-wise sequence identity≥ 40% because MINI did not have enough scale to eliminate redundancy. To avoid the contingency of negative sample selection, we repeated the above processes 5 times to form ...
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In the assessment of the Filipino version, there was a poor correlation between FES-I and TUG scores (r = 0.25) and FES-I scores failed to discriminate the participants with or without fall risk classified by the short-form Physiological Profile Assessment [32]. One explanation was the ...
Compared with the traditional oral administration form, injection administration is basically superior in terms of both biological availability and therapeutic effects. However, few researches have focused on the traditional Chinese medicinal injection due to the complicated constituents and the intricate mecha...
Schnee C, Köllner TG, Held M, Turlings TCJ, Gershenzon J, Degenhardt J: The products of a single maize sesquiterpene synthase form a volatile defense signal that attracts natural enemies of maize herbivores. Proceedings of the National Academy of Sciences of the United States of America. 2006...
We show that SOX4, EZH2 and HDAC3 form a co-repressor complex that binds to the miR-31 promoter, repressing miR-31 through an epigenetic mark by H3K27me3 and by histone acetylation. Clinically, when compared to normal adjacent tissues, esophageal tumor samples show upregulation of SOX4, ...
form inactive forms, which cannot be differentiated from vegetative cells using an DNA based metabarcoding approach. Fungal communities in our study were less diverse than bacterial communities in NSM soil, as previously showed elsewhere [39,49], and the soil autoclaving had almost eradicated them ...