The use of probiotics could promote the balance of the subgingival microbiota to contribute to periodontal health. This study aimed to identify the potential of bacteria commonly associated with healthy periodontal tissues as probiotic candidates. A syst
Protein-DNA interactions are essential for fundamental biological activities including DNA transcription, replication, packaging, repair and rearrangement. Proteins interacting with DNA can be classified into two categories of binding mechanisms - sequen
Much of research on household catastrophic medical expenses in China has focused on less developed areas and little is known about this problem in more developed areas. This study aimed to analyse the incidence and determinants of catastrophic medical ex
Predicting enzyme active-sites in proteins is an important issue not only for protein sciences but also for a variety of practical applications such as drug design. Because enzyme reaction mechanisms are based on the local structures of enzyme active-sit
of identifying new diagnostic markers and therapies to enable the initiation of early intervention [2]. The most prevalent form of PC is pancreatic ductal adenocarcinoma (PDAC) [3]. Tumor growth is triggered by mutations and subsequent inactivation of tumor suppressor genes that cooperate withKRAS...
The study protocol was approved by the Clinical Research Ethics Committee of the San Carlos Clinical Hospital (Madrid, reference number “C.P. - C.I. 12/152-E”. All subjects were informed of the characteristics of the study and agreed to participate by signing an informed consent form. Cla...
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?db=m&form=6&Dopt=r&uid=3964028Google Scholar 34. Murray CJL, Lopez AD. The Global Burden of Disease: A Comprehensive Assessment of Mortality and Disability From Diseases, Injuries, and Risk Factors in 1990 and Projected to 2020. ...
and α and β defensins [96] and these factors can disrupt the membranes or cell wall to kill the pathogenic bacteria and maintain homeostasis in the intestine [97,98]. Additionally, intestinal goblet cells release mucin to form a protective layer of mucus at the top of the intestinal ...
A permanent complex is usually very stable and thus only exists in its complexed form. In contrast, a transient complex can exist in separated state. The method of differentiating the transient complexes and permanent complexes is same as the one used by Ofran and Rost [46]. The guild lines...
Two reviewers independently extracted data, and the third reviewer checked the consistency between them. A standard form was used; the extracted items included author, study design, sample size, publishing date, country, case number, age, gender, intervention method, dosages and type of anesthesia...