Amino acids (AAs) are one of the primary metabolic substrates for cardiac work. The correlation between AAs and both atrial fibrillation (AF) and aging has been documented. However, the relationship between AAs and age-related AF remains unclear. Initial
To gain more mechanistic insights into CRS-induced Kyn elevation in the PFC, large neutral amino acid transporter 1 (LAT1), a key transporter responsible for delivering larger, neutral amino acids and Kyn across the blood–brain barrier (BBB) from the peripheral circulation [32,33,34], was ...
Hyaluronic acid (HA) has gained significant attention due to its unique physical, chemical, and biological properties, making it widely used in various industries. This study aimed to screen bacterial isolates for HA production, characterize favorable fe
it appears thatE. coliuses different strategies to adapt to and colonize these two environmentally different niches (Fig.4). Bladder-enriched functions included those associated with iron metabolism, hippuric acid hydrolase, and a uric
1-aminocyclopropane-1-carboxylic acid (ACC) in plants: more than just the precursor of ethylene! 2014;5:1–11. Li D, Mou W, Van de Poel B, Chang C. Something old, something new: conservation of the ethylene precursor 1-amino-cyclopropane-1-carboxylic acid as a signaling molecule. Curr...
LC/MS analysis of amino acid content in CFSs (Supplementary Fig. 9) revealed that the ADI-dependent pathway is fully functional in all tested strains. In the Lc4 strain, the ADI release is not likely connected to different regulation and expression of these proteins under stress conditions [...
Aromatic amino acid aminotransferase CD: Crohn’s disease CFS: Cell-free supernatant CLP: Common lymphoid progenitor CMT: Colonic microbiota transplantation DAI: Disease activity index GSEA: Gene set enrichment analysis IAA: Indole-3-acetic acid IAAH: Indoleacetamide hydrolase IBD: Inflamm...
Table 2 Amino acid set for pathogenicity identification Full size table Fig. 3 Signature positions in the 11 viral proteins. A Profile of 40 signature positions from positive samples of IBV. B Profile of 40 signature positions from negative samples of IBV. The x-axis represents the signature ...
Notably, THCAS evolves from the ancestor gene CBDAS, and they have a high degree of similarity at the nucleotide and amino acid levels [36, 37]. In the genome, THCAS and CBDAS are closely related and located in the retrotransposon enrichment region [38, 39]. Multiple THCAS and CBDAS ...
interactions between Chinese medicines and the host and intestinal flora. Notably, their findings have demonstrated that the crucial mechanism underlying the treatment of ulcerative colitis with oral 5-Amino Salicylic Acid (5-ASA) involves its regulatory effect on intestinal flora and bile acid ...