(Units) the derived SI unit of frequency; the frequency of a periodic phenomenon that has a periodic time of 1 second; 1 cycle per second. Symbol:Hz [C20: named after Heinrich Rudolph Hertz] Hertz (hɜːts;Germanhɛrts) n
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Population allele frequency is crucially important for accurate interpretation of known and novel variants in medical genetics. Recently, several large allele frequency databases, such as the Genome Aggregation Database (gnomAD), have been created to serve as a global reference for such studies. ...
Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population A measure of population subdivision based on microsatellite allele frequencies. Relationships between the carbon-oxygen stretching frequencies of carboxylato complexes and the type of carboxylate coordination ...
Frequency of an allele Frequency of an allele Frequency of Blastocysts with Morphological Alterations frequency of breathing frequency of breathing frequency of compounding Frequency of Drinking Days Frequency of Earth-Sized Inner Planets Frequency of Gobbledygook Frequency of Inherited Disorders Database Frequ...
In addition, the minor allele frequency of SNPs in the reference population affected the accuracy. The accuracy increased as the size of the reference ... Y Uemoto,S Sasaki,Y Sugimoto,... - 《Animal Genetics》 被引量: 12发表: 2015年 ...
Comparisons of reported CYP2C9 allele frequencies in Koreans. n *1 CYP2C9 allele frequency *2 *3 *13 Reference 3592 716 1148 590 0.952 (0.945–0.959) 0.934 (0.916–0.952) 0.989 (0.983–0.995) 0.947 (0.929–0.965) 0.000 (0.000–0.000) 0.000 (0.000–0.000) 0.000 (0.000–0.000) 0.000 ...
However, these simplified assumptions may not portray the many factors affecting pooled sequencing data quality, such as PCR amplification during target capture and sequencing, reference allele preferential bias, and others. As a result, the properties of the observed data may differ substantially from...
We analyzed a total of 54 simulated data with various sequencing depths and variant allele frequencies (VAFs), two reference data, and Horizon Tru-Q sample data. The results showed that the UMI-based callers, except smCounter2, outperformed the raw-reads-based callers regarding detection limit...
Here we report a method for the accurate tracking of thousands of distinct mutations that requires substantially fewer reads per locus than conventional hybrid-capture duplex sequencing. The method, which we named MAESTRO (for minor-allele-enriched sequencing through recognition oligonucleotides), combines...