How to calculate allele frequency in a population? What does an allele frequency measure? What is meant by allele frequency? How is a recessive allele different from a dominant allele? What is the relationship between a gene pool and allele frequency? Describe a scenario where the recessive alle...
To calculate the expected effect of a double perturbation on each parameter, fractional changes of the individual perturbations are multiplied, analogous to the way phenotypic growth effects caused by pairwise genetic interactions are assessed36. The error bars are calculated by error propagation of ...
Analysing the distribution of crossover-associated MLH1 signal along mole vole male sex chromosomes, we found a high frequency of foci close to the asynaptic zone and a lower frequency of signals in telomeric areas. At a distance of 65–75% of the length of Ss1 (counting from the telomere...
This was demonstrated by the simultaneous detection of the mutation underlying Miller syndrome by WGS of a family consisting of two affected siblings and their parents with the added bonus of being able to calculate a human intergenerational mutation rate of approximately 1.1 × 10-8 per position ...
was used to calculate the polymorphism information content (PIC) and to create input files for the software GENEPOP ver. 4.2 (Raymond and Rousset1995; Rousset2008) to conduct Hardy–Weinberg Equilibrium (HWE) testing; dememorization number = 5000; number of batches = 1000; number of ...
(mol. mass. cutoff 3 kDa, concentrator Pierce PES 3K, Thermofisher). The concentration factor was noted for each fluid and used in the calculation of the results. The average concentration factor was 7 with a range from 4 to 10 and it was used to calculate non-concentrated levels. A ...