Free light chainsfree light chainHaving developed serum free light chain (FLC) assays and initiated many of the early evaluations, we would welcome the opportunity to comment upon some of the issues raised in the November edition of the Annals of Clinical Biochemistry.1–3G P Mead, H D Carr...
KAPPA LIGHT CHAINS (FREE) information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses, prices, suppliers, SDS and more, available at Chemicalbook.
f Free Light Chains The Clinical Significance of Free Light ChainsThe Clinical Significance of Free Light Chainsdoi:10.3109/00365518109097510NoneTaylor & FrancisScandinavian Journal of Clinical & Laboratory Investigation
PB2189 FREE LIGHT CHAINS IN MULTIPLE MYELOMA: IS IT TIME TO EXTEND THEIR APPLICATION?doi:10.1097/01.HS9.0000567236.65953.60Markovic, U.Leotta, V.Giubbolini, R.Romano, A.Del Fabro, V.Di Raimondo, F.Conticello, C.HemaSphere
Free light chains will normally be present in the blood at low levels, with a kappa/lambda ratio of approximately 0.26 to 1.65 for individuals with normal kidney function. Increased kappa free light chains and an increased kappa/lambda ratio may be seen with plasma cell disorders that produce ...
Free Light Chains (FLCs) are immunoglobulin light chains which are circulating in serum in a free state (unbound). There are two types of immunoglobulin light chain produced in humans, designated kappa (κ) and lambda (λ). The quantification of serum FLC is used as an aid in the diagnosi...
A new immunoassay for free light chain measurements has been reported to be useful for the diagnosis and monitoring of monoclonal light chain diseases and nonsecretory myeloma. We describe experience with and some potential pitfalls of the assay.The assay was assessed for precision, sample type and...
Kappa free light chains (KFLC) index has been described as a reliable marker of intrathecal immunoglobulin G (IgG) synthesis in multiple sclerosis (MS), resulting even more accurate than IgG index to discriminate MS from other neurological diseases1,2,3. Immunoglobulin free light chains (FLC),...
plating on the chains ensures extremely strong corrosion protection. Thanks to the special sinter lubrication, maintenance-free MEGAlife chains need no relubrication during their product life cycle. This means that the chains need 3/4 less lubricant compared with normal chains with initial lubrication...
Plasma cells, normal as well as clonal, secrete small amounts of kappa or lambda free light chains and these are quickly eliminated by the kidneys resulting in relatively low levels of circulating serum free light chains. However, in the presence of clonal plasma cells as with MGUS or MM, ...