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Both MS2 and Qβ VLPs have been produced with non-standard amino acid enabled click chemistry, allowing proteins, nucleic acids, and polymer chains to be attached to the surface of the VLPs [89]. In the last year, the E. coli platform has enabled the production of the largest biological ...
The variable regions of the heavy and light chains contain a binding domain that interacts with an antigen while, depending on the isotype, the constant region(s) may mediate the binding of the immunoglobulin to host tissues or factors. Also included in the definition of “antibody” as used ...
The CPT1 inhibitor etomoxir remarkably improved the sensitivity of drug-resistant lung adenocarcinoma cells to PTX [181]. These outcomes highlight a novel role of disrupted fatty acid metabolism in tumor lipogenesis, suggesting that key enzymes catalyzing fatty acid synthesis may be putative targets ...
This is likely due to some polymer chains rearrangements taking place as a result of the addition of an ethanol to the aqueous dispersions and its subsequent removal under vacuum combined with the process of the drug solubilization into the preformed PIC micelles. The zeta potential measurements on...
The population balance equations (PBEs) are given in Table 2, where the definitions of the zero- and first-order moments of the chain length distribution of the active chains (λ0 and λ1, respectively) and of their number average molecular weight (MnR) are as follows: ∞λ0 = ∑ R·...
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