Biology definition: Aframeshift mutationis a type ofgene mutationin which the addition or deletion of one or morenucleotidescauses a shift in thereading frameof thecodonsin themRNA, which may lead to the alteration in theamino acidsequence at proteintranslation.Variant:frame shift mutation.Synonyms...
Any mutation of the HEXA gene will cause Tay-Sachs disease, and more than 80 such mutations have been identified. One of the more common mutations that causes Tay-Sachs disease is a single-nucleotide deletion frameshift mutation (the 1510th nucleotide, a cytosine (C), is removed). Which is...
The two brothers with AHC and HHG caused by a novel DAX1 mutation, reached tall final heights, despite of the disadvantageous prednisolone treatment during their childhood. We assume that the long-term lack of the sexual hormone substitution was a significant reason of their above average height...
Step-by-Step Text SolutionStep 1: Definition of Point Mutation - Point mutation is defined as a mutation that involves a change in a single nucleotide in the DNA sequence. This alteration can occur through subs
In LD, the dysregulation of lncRNA expression might have a different biological meaning. In the presence of specific FOXC2 variations, such as frameshift mutations, the decrease in FOXC2-AS1 expression might contribute to the reduction in FOXC2 mutant proteins production. This mechanism might ...
In LD, the dysregulation of lncRNA expression might have a different biological meaning. In the presence of specific FOXC2 variations, such as frameshift mutations, the decrease in FOXC2-AS1 expression might contribute to the reduction in FOXC2 mutant proteins production. This mechanism might ...