ReFrame is not only able to quantify mutation frequency but also to distinguish indel mutation types, which is crucial for the prediction of the frame of the resulting frameshift peptides. As the translation of nucleotide into amino acid sequences is based on three base codons, every mutation in...
Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia. Breast Cancer Res. 2014;16(6):3419. Article PubMed PubMed Central Google Scholar Brnich SE, Abou Tayoun AN, Couch FJ...
tuberculosis examined and deficient in the production of phenolphthiocerol derivatives are natural mutants with a frameshift mutation in pks15/1 whereas a single open reading frame for pks15/1 is found in Mycobacterium bovis BCG, M. leprae, and strains of M. tuberculosis that produce phenolph...