将IRES-DTREGFP共表达结构插入到小鼠Foxp3基因终止密码子处。应用领域:DTR工具鼠*使用本品系发表的文献需注明: Foxp3-IRES-DTRGFP mice (Cat. NO. NM-KI-190046) were purchased from Shanghai Model Organisms Center, Inc.. 验证数据 Fig1. Expression of GFP on Tregs in Blood and Spleen in Foxp3-IRES...
将IRES-DTREGFP共表达结构插入到小鼠Foxp3基因终止密码子处。 应用领域:DTR工具鼠 *使用本品系发表的文献需注明: Foxp3-IRES-DTRGFP mice (Cat. NO. NM-KI-190046) were purchased from Shanghai Model Organisms Center, Inc.. 验证数据 Fig1. Expression of GFP on Tregs in Blood and Spleen in Foxp3-...
To study this, we characterized endogenous foxp3 + cells in accelerated anti-glomerular basement membrane (GBM) nephritis by using foxp3 GFP reporter mice to track their responses in early and established disease. Further, diphtheria toxin was used to ablate foxp3 + Tregs in foxp3 DTR mice ...
C57BL/6 (B6), B6.SJL-Ptprca Pepcb/BoyJ (Cd45.1 mice), B6.129P2(Cg)- Rorctm2Litt/J (Rorg À / À ), STOCK Il-17atm1.1(icre)Stck/J, B6.129 Â 1-Gt(ROSA)26- Sortm1(EYFP)cos/J, B6.129(Cg)-Foxp3tm3(DTR/GFP)Ayr/J (Foxp3GFP) and C57BL/ 6-Foxp3tm1Flv/J (...
We found increased homing of GFP þ mo-MF to the CP and to the adjacent ventricular spaces following weekly GA treatment, as compared with vehicle-treated AD-Tg/CX3CR1GFP/ þ controls (Fig. 3f,g; a 2.0 ** 1.5 1.0 0.5 0.0 40 30 20 10 0 AD-Tg control + DTx 4 *** 3 ** ...
DT injection does not lead to a loss of epithelial integrity in our Foxp3-DTR models. Instead, Foxp3 expression is Treg-specific and ablation of Foxp3(+) Tregs leads to the induction of fatal autoimmune disorders. Autoimmunity can be reversed by the adoptive transfer of Tregs into depleted ...
将IRES-DTREGFP共表达结构插入到小鼠Foxp3基因终止密码子处。 应用领域:DTR工具鼠 *使用本品系发表的文献需注明: Foxp3-IRES-DTRGFP mice (Cat. NO. NM-KI-190046) were purchased from Shanghai Model Organisms Center, Inc.. 验证数据 Fig1. Expression of GFP on Tregs in Blood and Spleen in Foxp3-...
将IRES-DTREGFP共表达结构插入到小鼠Foxp3基因终止密码子处。 应用领域:DTR工具鼠 *使用本品系发表的文献需注明: Foxp3-IRES-DTRGFP mice (Cat. NO. NM-KI-190046) were purchased from Shanghai Model Organisms Center, Inc.. 验证数据 Fig1. Expression of GFP on Tregs in Blood and Spleen in Foxp3-...
品系全名 C57BL/6Smoc-Foxp3em3(IRES-DTREGFP)Smoc 目录号 NM-KI-190046 品系状态 活体 加入购物车 导出PDF 基因信息 基因名Foxp3 基因曾用名 sf; JM2; scurfin NCBI ID 20371 MGI ID 1891436 Ensembl ID ENSMUSG00000039521 Pubmed Foxp3 人类同源基因 FOXP3品系描述 将IRES-DTREGFP共表达结构插入到小鼠...
FIG. 13 shows potentials of fxDC and Foxp3-depleted DC to induce CD4/8 Treg, wherein pre-activated T cells of Foxp3GFPmice were co-cultured with splenic DCs (spDC), blood DCs (bDC) and fxDC-depleted (DT-treated) bDCs (bDC/DT) of TB Foxp3DTRmice (p3/E, for b-DCs), and the...