FOXD3-AS1 is a lncRNA and has been identified as a cancer-promoting gene in glioma. By analysing the FOXD3-AS1 expression in The Cancer Genome Atlas (TCGA) database, we found that FOXD3-AS1 has significantly high expression in breast cancer tumour comparing with the normal tissue. And ...
目的检测长链非编码RNA FOXD3-AS1(lncRNA FOXD3-AS1)在乳腺癌中的表达并观察lncRNA FOXD3-AS1对乳腺癌细胞迁移和侵袭的影响。 方法利用生物信息学的方法对肿瘤基因组图谱(TCGA)数据库中lncRNA FOXD3-AS1在乳腺癌中的表达量进行分析,应用实时定量反转录聚合酶链反应(RT-qPCR)技术检测lncRNA FOXD3-AS1在10例...
In addition, E74 like ETS transcription factor 1 (ELF1) stimulated FOXD3-AS1 transcription, and ELF1 silence-suppressed malignant phenotypes of OS cells were offset by FOXD3-AS1 upregulation. Overall, present work elucidated that ELF1-activated FOXD3-AS1 aggravated cell migration, invasion and...
FOXD3-AS1 is downregulated in NB tissues and cell lines, and ectopic expression ofFOXD3-AS1induces neuronal differentiation and decreases the aggressiveness of NB cellsin?vitroandin?vivo. Mechanistically, as a nuclear lncRNA, FOXD3-AS1 interacts with poly(ADP-ribose)?polymerase 1 (PARP1) to...
Risk-Associated Long Noncoding RNA FOXD3-AS1 Inhibits Neuroblastoma Progression by Repressing PARP1-Mediated Activation of CTCF Molecular therapy : the journal of the American Society of Gene Therapy (2018) -4Comments pubmed: 29398485 doi: 10.1016/j.ymthe.2017.12.017 issn: 1525-0016 issn: 1525...
Retracted: Evaluation of lncRNA FOXD3-AS1 as a Biomarker for Early-Stage Lung Cancer Diagnosis and Subtype IdentificationThis article retracts the following: Evidence-Based Complementary and Alternative Medicine First published: 04 October 2023 https://doi.org/10.1155/2023/9782478...
沉默FOXD3-AS1或过表达miR-335-3p后,PTEN表达水平降低,细胞活力升高,细胞凋亡率降低,CAT,SOD活性升高,MDA含量降低(P<0.05).抑制miR-335-3p可逆转沉默FOXD3-AS1对H_(2)O_(2)处理的PC12细胞损伤的作用.FOXD3-AS1靶向miR-335-3p,miR-335-3p靶向PTEN.结论沉默FOXD3-AS1通过调控miR-335-3p/PTEN轴减轻H_...
High FOXD3-AS1 expression was significantly associated with poor differentiation of tumor tissues, increased tumor size and positive lymph node metastasis. FOXD3-AS1 overexpression significantly increased CC cell proliferation, migration and invasion compared with the negative control (NC) group, whereas...
It corrects an error in Figure 5 of the article titled "LncRNA FOXD3-AS1 promotes the malignant progression of nasopharyngeal carcinoma through enhancing the transcription of YBX1 by H3K27Ac modification." The authors apologize for the error and state that it does not affect ...
Functionally, FOXD3-AS1 promoted oxidative stress-induced lung epithelial cell death. In human lung epithelial cells, the microRNA-150 (miR-150) was identified to interact with FOXD3-AS1; this finding was confirmed using the luciferase reporter assays. Consistently, mutation on the miR-150 ...