Nanostructured lipid carriersPickering functionalitySolid lipid nanoparticlesLipid nanoparticles have been widely investigated for their use as either carriers for poorly water soluble actives or as (Pickering) emulsion stabilisers. Recent studies have suggested that the fabrication of lipid nanostructures that...
The aim of the present study was to develop, characterize and optimize a solid lipid nanoparticle system to deliver budesonide to the lungs. Budesonide-loaded solid lipid nanoparticles were prepared by the emulsification-solvent diffusion method. The impact of various processing variables including ...
Lipid nanoparticles (LNPs) are nano-sized particles that are mainly composed of lipids. Traditionally, LNPs are referred to as liposomes, lipoplexes, solid lipid nanoparticles, nanostructured lipid nanoparticles, microemulsions, and nanoemulsions, which are mainly used in the delivery ...
This study was designed to prepare AE-loaded solid lipid nanoparticles (AE-SLNs) in an attempt to improve the anti-cancer efficacy of AE. The AE-SLNs were prepared with optimized prescription using high pressure homogenization (HPH) technique. Ultimately, the AE-SLNs showed stable particle ...
ObjectivesThe purpose of this study was to formulate and characterize metoclopramide solid lipid nanoparticles (MCP-SLNs) and incorporating it into suppository bases for treatment of nausea and vomiting, produced with chemotherapeutic agents, using one dose per day.MethodsMCP-SLNs was prepared using hi...
Solid lipid nanoparticles for nose to brain delivery of donepezil: formulation, optimization by box-behnken design, in vitro and in vivo evaluation. Artif Cells Blood Substit Biotechnol 2017:14. DOI: 10.1080/21691401.2017.139487.
The purpose of this study was to formulate and characterize metoclopramide solid lipid nanoparticles (MCP-SLNs) and incorporating it into suppository bases for treatment of nausea and vomiting, produced with chemotherapeutic agents, using one dose per day. ...
While they protect the water content of the epidermis by increasing skin occlusion, maintain the smoothness and elasticity of the skin, enhance the efficacy of the active substance by penetrating into the deep layers of the skin. Semi-solid lipid nanoparticles, which are the latest generat...
Solid lipid nanoparticles (SLN) are colloidal carrier systems representing a promising approach as a drug delivery system for topical application. Therefore, the objective of this investigation was to develop Meloxicam Solid lipid nanopa... RM Khalil,AA Elbary,MA Kassem,... 被引量: 8发表: 2013...
Solid lipid nanoparticles (SLNs) loaded with Cyclosporine A using glyceryl monostearate (GMS) and glyceryl palmitostearate (GPS) as lipid matrices were prepared by melt-homogenization using high-pressure homogenizer. Various process parameters such as homogenization pressure, homogenization cycles and form...