A procedure for Drug formulation comprising mixing particles of a vehicle with a solution of a drug monohydrochloride [R - (Z)] - alpha - (alpha - (metoximiimino) - 1-azabicyclo [2.2.2] oct 3 - il) acetonitrile in water in unacan amount of 1 - 3% by weight of total mixture ...
Formulation design of a highly hygroscopic drug (pyridostigmine bromide) for its hygroscopic character improvement and investiga- tion of in vitro/in vivo ... YT Huang,TR Tsai,CJ Cheng,... - 《Drug Development & Industrial Pharmacy》 被引量: 30发表: 2007年 Formulation design of a highly hyg...
Drug release from prepared formulations using HPMC was dependent on concentration of super-disintegrant and swelling polymer used in loading dose layer and also on amount of HPMC compressed on core tablet; in case of compritol 888 ATO containing tablets, drug release was dependent on amount of ...
The invention relates to a pharmaceutical combination comprising a drug for treating sexual disorders, and albumin. The invention also relates to a pharmaceutical formulation for treating sexual disorders, which contains a combination of... AA Choza Romero 被引量: 0发表: 2017年 Development of a Lyo...
Formulation has become one of the most overlooked parts of drug development, but it can be the difference between an effective medicinal product and a very expensive placebo. A successful robust medicinal product is the result of a controlled set of interactions between the API, excipients and ...
Status of Safety Pharmacology and Present Guidelines "The adverse drug reactions which the standard toxicological test procedures do not aspire to recognize most of the functional side-effects. Clinical experience indicates, however, that these are much more frequent than the toxic reactio... FJ Hock...
Formulation considerations for the development of medications with abuse potential. Drug Alcohol Depend. 2006;83(1):15-22. RS Mansbach,RA Moore - 《Drug & Alcohol Dependence》 被引量: 36发表: 2006年 Managing severe pain and abuse potential: the potential impact of a new abuse-deterrent ...
The study of the absorption, distribution, metabolism, excretion and interactions of a drug. PEGylation The covalent binding of polyethylene glycol (PEG) to a protein. EPITOPE An alternative term for an antigenic determinant. These are particular chemical groups on a molecule that elicit a specific...
Drug formulation is a cornerstone of modern medicine, turning raw active ingredients into consumable, effective therapies. This critical phase in drug development ensures that medications are safe, effective, and user-friendly. Here Ningfeng Fiona Li, founder and CEO of VasoDynamics, explores the ...
The objective of this study was to develop and manufacture a stable parenteral formulation for Aspirin, a non steroidal anti-inflammatory agent. The solubility and stability of the drug was determined. Solubility studies suggested that Aspirin exhibited poor aqueous solubility but showed appreciable solub...