On 1 April 1918, the Royal Air Force was formed from fhe amalgamation of the Royal Flying Corps (RFC) - run by the British Army and the Royal Naval Air Service (RNAS) - operated by the Royal Navy. The new combined independent force was controlled by the newly formed government-controlled...
The present study examined whether preglomerular arterioles of the rat produce 20-hydroxyeicosatetraenoic acid (20-HETE) and whether 20-HETE is vasoactive on these vessels. Raf preglomerular arterioles produced 20-HETE (4.8 +/- 1.0 pmol.min-1.mg-1, n = 7) and, to a lesser extent, 14-,...
The intriguing host innate immune response: novel anti-parasitic defence by neutrophil extracellular traps pathogens in a controlled process which depends on reactive oxygen species (ROS) and the induction of the Raf-MEK-ERK-mediated signalling pathway cascade... C Hermosilla,TM Caro,LMR Silva,.....
Together with the finding that the Ras-binding domain of the protein kinase c-Raf, whose binding site on Ras overlaps that of the GAPs, did not induce formation of such a complex, this result suggests that GAP and neurofibromin stabilize the transition state of the GTPase reaction of Ras....
Retinoic Acid (RA) treatment induces disease remission of Acute Promyelocytic Leukaemia (APL) patients by triggering terminal differentiation of neoplastic cells. RA-sensitivity in APL is mediated by its oncogenic protein, which results from the recombin
Furthermore, the hydride complexes exhibit significant rotational motions associated with anharmonic librations at room temperature, which are often discussed in relation to the translational diffusion of cations in alkali-metal dodecahydro-closo-dodecaborates and strongly point to the emergence of a ...
& Li, W. (1994) Interferons block protein kinase C-dependent but not independent activation of Raf-1 and mitogen activated protein kinases and mitogenesis in NIH 3T3 cells, Mol. Cell. Biol. 14, 8018–8027. 17 Kessler, D. S., Pine, R., Pfeffer, L. M., Levy, D. E. & Darnell,...
Abstract 21: Selective and potent inhibitors of the mutant B-Raf pathway paradoxically stimulate the MAPK pathway in wild-type B-Raf cells B-Raf is a member of the Raf family of serine/threonine kinases, which also include A-Raf and C-Raf. While all 3 Raf kinases stimulate the MAPK signa...
R Drehmann,T Grund,T Lampke,B Wielage,K Manygoats,T Schucknecht,D Rafaja 摘要: The metallization of ceramics by means of cold gas spraying (CGS) has been in the focus of numerous publications in the recent past. However, the bonding mechanism of metallic coatings on non-ductile ...
B, Microelectronics and nanometer structures: processing, measurement, and phenomena: an official journal of the American Vacuum Society 被引量: 9发表: 1999年 Spectroscopic ellipsometry investigation of nickel silicide formation by rapid thermal process Yaozhi Hu, Sing Pin Tay, Spectroscopic ellipsometry...