Sun T-T, Green H (1976) Differentiation of the epidermal keratinocyte in cell culture: Formation of the cornified envelope. Cell 9:511–521Sun T-T, Green H (1976) Differentiation of the epidermal keratino cyte in cell culture: Formation of the cornified envelope. Cell 9:511–521...
This article would provide a novel opportunity to understand the allergic/autoimmune disorders from the viewpoint of non-classical immune cells. 展开 关键词: atopy cornified cell envelope psoriasis skin barrier stratum coenrum DOI: 10.2177/jsci.40.416 年份: 2017 ...
The level of the cellular retinoic acid binding protein (CRABP) is considerably increased in its presence. Butyrate does not interfere with the binding of retinoids to their cellular binding proteins. Our observations suggest that sodium butyrate stimulates cornified envelope formation via the induction...
The cornified cell envelope (CE) is an insoluble, highly resistant structure formed beneath the plasma membrane of differentiating keratinocytes. It consists of various crosslinked precursor proteins, including involucrin and loricrin. However, neither the normal assembly process of CE nor its alteration...
At the completion of this process, the keratinocytes become enucleated and form the cornified layer, the surface layer of the skin. The highly cross-linked protein-lipid envelope and extracellular lipids in the cornified layer along with cell-cell adhesions in the granular layer are required for...
and the large number of family members identified to date suggest that the pancornulins and other spr-1-related proteins may be more important in cornified envelope formation than previously considered, perhaps functioning as “bridge” molecules during the early phases of cornified envelope assembly...
Expression of loricrin is negatively controlled by retinoic acid in human epidermis reconstructed in vitro . In epidermis, the last steps of keratinocyte differentiation are characterized by the covalent cross-linking of cornified envelope precursors such as inv... T Magnaldo,F Bernerd,D Asselineau,...
Akiyama M,Matsuo I,Shimizu H.Formation of cornified cell envelope in human hair follicle development.Br J Dermatol. 2002Akiyama M, Matsuo I, Shimizu H. Formation of cornified cell envelope in human hair follicle development. Br J Dermatol. 2002; 146(6):968-976. [PubMed: 12072064]...
In addition, cornified envelope formation was ob- served for a number of related anthracenones at concentrations as low as 1-5 碌M. In general, compounds containing benzoyl substit- uents, independent of the position in the anthralin nucleus, were more potent than those having benzyl ...
cornified envelopedithranolHaCaT cellkeratinocyte differentiationThe ability of the antipsoriatic anthralin to induce HaCaT keratinocyte differentiation was investigated and correlated with its potency to inhibit proliferation of keratinocytes. To determine the structural requirements for this effect, anthralin ...