The zebrafish has become an important model organism to study myelination during development and after a lesion of the adult central nervous system (CNS). Here, we identify Claudin k as a myelin-associated protein in zebrafish and determine its localization during development and adult optic nerve ...
The , and hence the myelin-forming (i.e. Schwann in the PNS and oligodendrocytes in the CNS), have been a crucial acquisition of . The major function of my... B Zalc - 《Novartis Found Symp》 被引量: 31发表: 2006年 Cutting the first 'teeth': a new approach to functional analysis...
Answer to: Schwann cells form the myelin sheath around multiple axons at once and the neurilemma which aids in axon regeneration after injury. a...
Molecules that are found in the extracellular environment at a CNS lesion site, or that are associated with myelin, inhibit axon growth. In addition, neuro... ME Selzer - 《Lancet Neurology》 被引量: 294发表: 2003年 Axonal projections between fetal spinal cord transplants and the adult rat ...
The 46-kDa antigen reacting with the autoantibody exhibited the same Mr and pI as the small isoform of CNP on two-dimensional gels and showed a similar enrichment in purified CNS myelin. The autoantibody has very high affinity for CNP1 and is capable of detecting the very low amounts of ...
To test this concept, we examined the effects of overexpressing the long form of human FLICE-inhibitory protein, a potent inhibitor of death receptor-mediated apoptosis, in myelin oligodendrocyte glycoprotein-induced EAE in DBA/1 mice. We found that overexpression of the long form of human FLICE...
Smaller signaling compartments are established by astrocytes that tile the synaptic areas in the brain6,7,8. Oligodendrocytes insulate single segments of up to 20 different axons by forming myelin sheets around them9. Moreover, oligodendrocyte progenitor cells act as innate immune cells and ...
Congenital hypothyroidism is characterized by axons that fail to become wrapped with myelin during development. The resulting effect on neurotransmission in the developing fetus would be: a. decreased neuronal conduction speed. b. inability of the fetus t ___ is a genetic ...
ADEM's pathogenesis isn't fully understood, the leading theory suggests an antigenic analogy between myelin antigens and the pathogen responsible for ADEM [9], which explains why cases of ADEM have been reported both in patients with COVID-19 and subjects vaccinated with the AZD1222 COVID-19 ...
What cells form myelin in the spinal cord? Which structure surrounds the connection between the spinal cord and the brain? What type of nerve fibers are found in the anterior roots of the spinal cord? a) Motor. b) Sensory. c) Both. Identify the CNS co...