Folate is the anionic form of folic acid. At physiological pH the acid-base form is folate. Very often, the term “folic acid” refers to the fully oxidized synthetic compound used in dietary supplements, whereas “folate” refers to the various tetrahydrofolate derivatives naturally present in ...
The most important manifestation of alcohol toxicity is anaemia, but abnormalities in platelets and white blood cell production are also observed. One of the earliest indications of the ability of ethanol to interfere in cellular metabolism was the observation by Gram (1884) of macrocytosis in ...
Folate (folic acid) is required for normal blood formation and neurological health. Its deficiency is common among low socioeconomic groups, especially during pregnancy, infancy, and childhood (Box 8.5). Deficiency is common in alcoholics, owing to malnutrition or impaired absorption. Alcoholics with...
Up to 1 mg folic acid daily; some patients may require larger doses. Usual maintenance dosage: 0.4 mg daily. Usual maintenance dosage for pregnant and lactating women: 0.8 mg daily. Higher maintenance dosages may be required in alcoholics, patients with hemolytic anemia, chronic infections, and...
A central origin was evoked; however, the role of the folic acid deficiency could not explain the macrocytosis, the mechanism of which remains to be elucidated. Haematological parameters in alcoholics--early detection More results ► Medical browser ? ▲ folds of uterine tubes Foley Foley cathete...
Alcoholics may have decreased absorption, impaired storage, and diminished the ... MA Korsten,CS Lieber - 《Nutrition in the Middle & Later Years》 被引量: 2发表: 1983年 Folic acid deficiency in the Irish elderly. Discusses the abstract of the research article `Folic Acid Deficiency in the...
This deficiency can result from diets devoid of raw fruits, vegetables or other foods rich in folic acid, as may be the case with chronic alcoholics, drug addicts, the elderly or persons of low socioeconomic status, etc. In addition, low serum folate during pregnancy has been associated with...
The levels of vitamin B12 and folic acid in the serum of 50 male alcoholics admitted in the Kasturba Gandhi Memorial Deaddiction, Rehabilitation and Research Centre, Coimbatore, Tamil Nadu, India, were determined. For comparison, age-matched nonalcoholics were also studied as controls. Serum ...
Folate derivatives (FDs) are important cellular cofactors in the synthesis of nucleotides required for DNA replication, in the synthesis of the amino acids glycine and methionine and in the metabolism of histidine, glutamic acid and serine. These factors are also required for the initiation of prote...
Folic acid in serum and cerebrospinal fluid ofchronic alcoholics and methamphetamine addicts. Drug Alcohol Depend 1981:7:193-9.Y. Nakazawa et al., Folic acid in serum and cerebrospinal fluid of chronic alcoholics and metamphetamine addicts. Drug Alcohol Depend., 7 (1981) 193 - 199....