folic acid antagonists such as methotrexate); the administration of anticonvulsants, such as diphenylhydantoin, primidone, and barbiturates; alcohol consumption and, especially, alcoholic cirrhosis; and the administration of pyrimethamine and nitrofurantoin. ...
Folate derivatives (FDs) are important cellular cofactors in the synthesis of nucleotides required for DNA replication, in the synthesis of the amino acids glycine and methionine and in the metabolism of histidine, glutamic acid and serine. These factors are also required for the initiation of prote...
. Folic acid was associated with higher risks of having three or more adenomas and of noncolorectal cancers. Sex, age, smoking, alcohol use, body mass index, baseline plasma folate, oraspirinallocation played no crucial role in the modification of results. They concluded that folic acid at ...
Folate deficiency may result from increased loss of folate, as in renal dialysis and/or interference with metabolism (e.g., folic acid antagonists such as methotrexate); the administration of anticonvulsants, such as diphenylhydantoin, primidone, and barbiturates; alcohol consumption and, especially,...
Folate deficiency may result from increased loss of folate, as in renal dialysis and/or interference with metabolism (e.g., folic acid antagonists such as methotrexate); the administration of anticonvulsants, such as diphenylhydantoin, primidone, and barbiturates; alcohol consumption and, especially,...
Interactions Folate deficiency states may be produced by drugs such as antiepileptics, oral contraceptives, antitubercu- lous drugs, alcohol, and folic acid antagonists such as methotrexate, pyrimethamine, triamterene, trimetho- prim, and sulfonamides. In some instances, such as during methotrexate or...
ContextRecently, concern has been raised about the safety of folic acid, particularly in relation to cancer risk.ObjectiveTo evaluate effects of treatment
Dietary folate intake, alcohol and risk of breast cancer in a prospective study of postmenopausal women. Epidemiology. 2001;12:420–8.PubMedView Article Lucock M. Folic acid: nutritional biochemistry, molecular biology and role in disease processes. Mol Genet Metab. 2000;71:121–38.PubMedView ...
Any medication taken in excess can have serious consequences. If you suspect an overdose of Metadoxine–Silymarin–L-Ornithine-L-Aspartate–Folic Acid–Pyridoxine HCl, seek medical attention immediately. What other drugs could interact with Metadoxine–Silymarin–L-Ornithine-L-Aspartate–Fol...
The invention relates to the uses of at least folic acid or a folate and tetrahydrobiopterin (BH4) or derivative thereof for treating or preventing cardiovascular of neurological disorders