The folate cycle and disease in humansFolate cycle kinetics in human breast cancer cells.Effects of folate cycle disruption by the green tea polyphenol epigallocatechin-3-gallateIntA mathematical model of the folate cycle: new insights into folate homeostasis.Folate cycle gene variants and chemotherapy...
Fowler, B. (2001) The folate cycle and disease in humans. Kidney Int. Suppl. 78, S221-S229Fowler, B. (2001) The folate cycle and disease in humans. Kidney Int.Suppl 78, S221-S229Fowler, B. The folate cycle and disease in humans. Kidney International. 2001. 59. 221-229....
网络释义 1. 叶酸循环 ...即蛋氨酸循环(methionine cycle)和叶酸循环(folate cycle),并将二循环联系在一起。 www.showxiu.com|基于 1 个网页
Curcumin is very efficient against numerous kinds of malignant cells, including breast carcinoma. Curcumin primarily achieves its anticancer properties by inhibiting the cell cycle and inducing apoptosis in malignant cells. Curcumin's low solubility in aqueous environments hinders its widespread use in canc...
Here we show that canonical longevity pathways converge on the one-carbon folate cycle, and cause a decrease in levels of the intermediate 5 methyl tetrahydrofolate (5MTHF) and various methionine cycle intermediates. Genetic manipulation of pathways enzymes and supplementation experiments reveal that ...
In this Review, we focus on the mitochondrial folate cycle. We discuss recent evidence that, in addition to supporting nucleotide synthesis, mitochondrial folate metabolism also contributes to metastasis through support of antioxidant defense, mitochondrial protein synthesis and the overflow of excess ...
In this Review, we focus on the mitochondrial folate cycle. We discuss recent evidence that, in addition to supporting nucleotide synthesis, mitochondrial folate metabolism also contributes to metastasis through support of antioxidant defense, mitochondrial protein synthesis and the overflow of excess ...
Collateral sensitivity to novel thymidylate synthase inhibitors correlates with folate cycle enzymes impairment in cisplatin-resistant human ovarian cancer... Collateral sensitivity to novel thymidylate synthase inhibitors correlates with folate cycle enzymes impairment in cisplatin-resistant human ovarian cancer ...
Using recombinant miRNA molecules produced and folded in living cells, a number of the top most effective miRNAs against NSCLC cell variability were identified, among which miR‐22‐3p, miR‐9‐5p and miR‐218‐5p were all predicted to interfere with folate cycle of one‐carbon metabolism. The...
In this regard, the folate cycle represents a “perfect model” of how genetics influences epigenetics. Gene variants in folate and folate‐related pathways can be considered risk factors for neurodevelopmental disorders and should therefore be assessed by genetic testing in pregnant women. High‐risk...