to 95 percent on normal skin cells HACAT of people, and thus, the recombinant lentivirus-based vector disclosed by the invention lays a good experimental foundation for further research related to the FLG gene and can be widely used for the in-vivo gene therapy and the gene functional research...
是Int J Radiat Oncol Biol Phys, Hum gene ther, J Cell Mol Med, Biomed Pharmacother, Cancer Manag Res,Molecular Biology Report, 华西医学等杂志评审专家。研究兴趣:放射性/免疫性心肺损伤,SBRT联合免疫治疗(PD-1/PD-L1,CAR-T)的生物学效应,SBRT与外泌体。 薛建新医生服务 挂号指引 图文咨询 暂未...
Title: The Functional GRHL3-FLG Axis Predicts Targeted Therapy Response in Head and Neck Cancer Background: Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous disease harbouring the most frequent hotspot mutations in the differentiation genes. Disruption of epithelial differentiation acts...
Functional enrichment analysis Gene Ontology (GO) and Gene set enrichment analysis (GSEA) was conducted. The infiltrating immune cells and the prediction of ICB between different subtypes group were explored using immuCellAI algorithm.\nResultsThe mutation genes Filaggrin (FLG) gene were identified. ...