For such patients intensive treatment options are limited.The FLAG (fludarabine, cytarabine and filgrastim) regimen is a non-anthracycline based chemotherapy useful for relapsed/refractory AML and as initial therapy for "fit" eligible patients. We present our experience using FLAG as first line ...
总体而言,地西他滨和伏立诺他联合 FLAG 化疗对患有 R/R AML 的儿科患者,尤其是具有表观遗传改变的患者具有良好的耐受性、生物活性和有效性。 原始出处: Pommert, L., Schafer, E.S., Malvar, J., Gossai, N., Florend...
我们于2006年3月2009年3月应用FLAG方案治疗复发或难治性AML患者37例,以评价FLAG方案的疗效,现将结果报道如下。1 资料与方法 1.1 一般资料 入选患者必须符合复发或难治性的AML诊断标准1,急性早幼粒细胞白血病除外,一般状况尚可,ECOG评分2分。主要包括:获得缓解后再次复发的患者;对初治诱导方案(DA方案等)化疗2个...
The purpose of the study was to evaluate the feasibility of conditioning regimen with sequential chemotherapy (FLAG-IDA), followed by Fludarabine (5 days) + Busulfan (3 days) by parallel analysis of patients with refractory acute myeloid leukemia (AML) from two transplantation centers in ...
文2:FLAG方案治疗复发难治性成人急性髓细胞白血病的护理氟达拉滨+阿糖胞苷+重组人粒细胞集落刺激因子(FALG方案)是目前用于 治疗 复发难治性急性髓细胞白血病(AML)疗效较为肯定的方案之一,其完全缓解率达到50%～80%[1],但FALG方案易致骨髓严重抑制,患者体能差,并发症多,良好的护理对患者恢复极其重要[2]。 总结...
Objective To investigate the efficacy and safety of fludarabine cytarabine and granulocyte colony stimulating factor (FLAG) chemotherapy on adult relapsed ... 刘宇宏,张艳,葛繁梅,... - 《肿瘤研究与临床》 被引量: 7发表: 2013年 IDA-FLAG方案治疗复发难治性白血病的临床研究 目的 探讨IDA-FLAG方案治疗...
Factors affecting outcome of salvage chemotherapy with FLAG +/- idarubicin for adults with relapsed/refractory AML To assess treatment response and overall survival (OS) in refractory or relapsed acute myeloid leukemia (R/R AML) patients treated by different common salv... A Boden,J Byrne,ED Gup...
(本文编辑:徐茂强)FLAG方案诱导FLT3突变急性髓系白血病缓解后IBu方案预处理的自体造血干细胞移植疗效分析王彪杨斌董伟民刘德亮凌云曹祥山EfficacyofFLAGasinitialinductionchemotherapyfollowedbyautologoushematopoieticstemcelltransplantatiOnafterIBuconditioningregimeninacutemyeloidleukemiawithFLT3mutationsWangBiao,Bin,DongWeimin,Liu...
(P0.05) there is no statistically significant with complication such as infection.Conclusion The improved FLAG regimen in treatment of refractory and relap sed acute myeloid leukemia(AML),which is not significantly lessen the complication of chemotherapy such as infection and bone marrow depression.but...
Sixteen patients had AML that was primary resistant to induction treatment, while 22 were relapsed, 11 after autologous bone marrow transplant (AuBMT), 8 less than 6 months from complete remission (CR) achievement, and 3 were second relapse from chemotherapy alone. Overall, 21 of 38 patients ...