(for example,chemotherapy drugsandblood, and so on) come into contact with auxiliary [...] legco.gov.hk legco.gov.hk 報道更指溶脂性高的液體(例如化療用藥劑和血液等)接觸含PVC質料的輔助醫療器材後會釋出更多塑化劑,經這 些醫療器材輸入體內,後果較進食受塑化劑污染的食品更嚴重,對早 產嬰兒、長期病...
Chemotherapy is a treatment used to kill cancer cells. It involves taking one or more of a type of drug that interferes with the DNA of fast-growing cells. These drugs are subdivided into specific classes such as alkylating agents, antimetabolites, anthracyclines and topoisomerase inhibitors. ...
The safety and tolerability profiles of dostarlimab plus chemotherapy in RUBY were generally consistent with the known safety profiles of the individual drugs.1 The EMA’s Committee for Medicinal Products for Human Use will start the formal review process to make a recommendation to the Eur...
Acute myeloid leukaemia (AML) is the most common form of leukaemia in young adults. Although 75-85% of patients will achieve complete remission after induc... Jonathan,Kell - 《Expert Opinion on Emerging Drugs》 被引量: 35发表: 2004年 Impact of allogeneic haematopoietic stem cell transplantation...
Bioluminescent bacterial biosensors can be used in a rapid in vitro assay to predict sensitivity to commonly used chemotherapy drugs in acute myeloid leukemia (AML). The nucleoside analog cytarabine (ara-C) is the key agent for treating AML; however, up to 30 % of patients fail to respond to...
New Insights on Success and Failed Drugs Chemotherapy: how to reduce its adverse effects while maintaining the potency? 03 February 2023 Kantarjian, H. M. et al. The cure of leukemia through the optimist’s prism.Cancer128, 240–259 (2022). ...
To generate the blood vessels required for bringing in nutrients and oxygen, cancer cells rely on the stroma that supports them to give pro-angiogenic signaling [85,86]. But stromal cells, like pericytes and fibroblasts, can be more vulnerable to the effects of chemotherapeutic drugs and can al...
Promising results have been shown for AT-406, an oral SMAC mimetic, in the sensitization of platinum based chemotherapy drugs such as carboplatin, cisplatin and paclitaxel in ovarian cancer cells [109]. Whilst AT-406 was an effective single agent for the treatment of OVCAR-8, SKOV-3, and OV...
Metronomic chemotherapy regimens were developed to optimize the antitumour efficacy of antiangiogenic agents and to reduce toxicity of antineoplastic drugs, but the effectiveness of this approach also relies on other mechanisms, such as the stimulation of the immune system. Investigating the pharmacokinetic...
Combo Tx for AML Patients Unfit for Intensive Chemotherapy Gets FDA Breakthrough StatusLea EslavaKimPharmD