bbln-1 is predicted to encode a single protein isoform of just 125 amino acids (aas) with a central coiled-coil domain ( aas 39–102) flanked by intrinsically disordered regions (Figure 1F). To investigate the localization pattern of BBLN-1, we engineered an endogenous BBLN-1::GFP fusion....
(NCX1), (F) ryanodine receptor (Ryr), (G) Ryr serine 2808, (H) Cav1.2, (I) Cav1.2 150 kDa, and (J) Cav1.2 75 kDa; n = 7–8 samples per protein from 8 patients. All analysis was performed using a two-sided Student’st-test. NS stands for not significant. Data shown are ...