Aging is a natural and irreversible process that is related to the accumulation of multifactorial degenerative processes characterized by morphological changes, functional decline, and metabolic disorders.11,12With the accelerating increase in the number of elderly people worldwide, aging is becoming the ...
Aging is a natural and irreversible process that is related to the accumulation of multifactorial degenerative processes characterized by morphological changes, functional decline, and metabolic disorders.11,12With the accelerating increase in the number of elderly people worldwide, aging is becoming the ...
(2005) Autophagy and aging: the importance of maintaining “clean” cells. Autophagy 1, 131–140. Google Scholar [133] J.P. Taylor, J. Hardy, K.H. Fischbeck Toxic proteins in neurodegenerative disease Science, 296 (2002), pp. 1991-1995 View in ScopusGoogle Scholar [134] Berger, Z., ...
CRISPR/Cas9 technology is currently undergoing clinical trials. This technology enables to support cancer therapy by enlisting a patient’s T cells at the NIH [20,21]. Furthermore, China granted ethical approval to a similar kind of clinical trial for gene therapy in human blood disorders ...
Aging and Disease, 11(2), 216–228. PubMed PubMed Central Google Scholar Ye, Q., Wang, H., Xia, X., Zhou, C., Liu, Z., Xia, Z., Zhang, Z., Zhao, Y., Yehenala, J., Wang, S., Zhou, G., Hu, K., Wu, B., Wu, C., Wang, S., & He, Y. (2020). Safety ...
Telomerase is a critical factor in CAR-T cell replication and overall function, and its abundance diminishes in cell division, aging, and disease.With reduced telomerase activity, CAR-T cells typically die or become aged, non-functional, and non-proliferating (senescent), leading to inhibited CAR...
Ionizing radiation-mediated premature senescence and paracrine interactions with cancer cells enhance the expression of syndecan 1 in human breast stromal fibroblasts: The role of TGF-β. Aging 2016, 8, 1650–1669. [Google Scholar] [CrossRef]...
which is cooked like a vegetable and has seeds like a fruit, stops cancer cells in their tracks, St. Louis University research found. Conducted in the laboratory and in mice, the research has not yet been tried in people, but points to bitter melon as a potential alternative therapy to co...
Understanding of telomerase activity may then bring a new insight into many serious clinical problems that we have to face in aging societies especially since telomerase might be also considered as a predictive marker maybe even in malignant transformation. It is still unclear whether telomerase ...
Patients with AP or ARDS may potentially benefit from testing for a variety of additional lncRNAs that have been proven to have diagnostic utility. Patients with AP have an elevated plasma plasmacytoma variant translocation gene 1 (PVT1) expression compared to healthy volunteers; this elevated express...