【疾病名】肝纤维化 【英文名】fibrosis of liver 【缩写】 【别名】hepatic fibrosis;肝纤维变性 【ICD 号】K74.0 【概述】 肝纤维化 (fibrosis of liver)是多种原因引起的慢性肝损害所致的病理改 变,表现为肝内细胞外间质成分过度异常地沉积,并影响肝脏的功能,是慢性 肝病发展到肝硬化必经之阶段。现认为肝纤...
【疾病名】肝纤维化 【英文名】fibrosisofliver 【缩写】 【别名】hepaticfibrosis;肝纤维变性 【ICD号】K74.0 【概述】 肝纤维化(fibrosisofliver)是多种原因引起的慢性肝损害所致的病理改 变,表现为肝内细胞外间质成分过度异常地沉积,并影响肝脏的功能,是慢性 肝病发展到肝硬化必经之阶段。现认为肝纤维化尚有逆...
Increased serum xylosyltransferase activity in patients with liver fibrosis. Clin. Chim. Acta 409, 123–126 (2009). 16. Götting, C. et al. Serum xylosyltransferase: a new biochemical marker of the sclerotic process in systemic sclerosis. J. Invest. Dermatol. 112, 919–924 (1999). 17. ...
The miR-19 family plays a significant role not only in cardiac fibrosis but also in the development of fibrosis in tissues of lungs [27], liver [28], intestine [29], and kidneys [30]. One of the key mechanisms through which the miR-19 family influences fibrosis is through the PTEN gen...
We defined liver fibrosis as: likely advanced fibrosis (FIB-4 > 3.25), indeterminate (FIB-4 range 1.45–3.25), unlikely advanced fibrosis (FIB-4 < 1.45). Primary outcomes were HFrEF and HFpEF (defined using ICD-9 diagnoses for HF, and EF extracted from electronic medical records using ...
Those who developed HCC were identified through electronic medical records using International Classification of Diseases (ICD) 9 and 10 codes until the end of September 2021. Results: During a median follow-up time of 3.7 years, 157 (11.7%) patients with NASH cirrhosis developed HC...
In addition, patients with late-stage cardiomyopathy who develop life threatening arrhythmias should be evaluated for and eventually provided with insertion of an implantable-cardio-defibrillator (ICD), in addition to pharmacological therapy and ERT[95]. The cell culture observations on the pro-fibrotic...
GuptaS,GhoshS,GuptaS, et al. Effect of curcumin on the expression of p53, transforming growth factor-beta, and inducible nitric oxide synthase in oral submucous fibrosis: a pilot study[J].J Investig Clin Dent,2017,8(4). doi:10.1111/jicd.12252. ...
CCL20 serves as a chemoattractant molecule for immature dendritic cells, which have been shown to produce many of the inflammatory molecules that mediate liver fibrosis. These data also point to hepatic stellate cells as a key cell type that may respond to lipid loading of the liver....
J Transl Med (2018) 16:108 https://doi.org/10.1186/s12967-018-1490-y Journal of Translational Medicine RESEARCH Open Access CCL20 is up‑regulated in non‑alcoholic fatty liver disease fibrosis and is produced by hepatic stellate cells in response to fatty acid loading Xin...