参考资料：标题：Regulation of FGF23 production and phosphate metabolism by bone–kidney interactions作者：Rafiou Agoro, Kenneth E. White期刊：Nature Reviews NephrologyDOI: 10.1038/s41581-022-00665-xPDF 下载链接：https://is.gd/sLRYzB — 完 —关注我，记得标星哦～
标题:Regulation of FGF23 production and phosphate metabolism by bone–kidney interactions 作者:Rafiou Agoro, Kenneth E. White 期刊:Nature Reviews Nephrology DOI: 10.1038/s41581-022-00665-x PDF 下载链接:https://is.gd/sLRYzB —完— 关注我,记得标星哦～...
Fukumoto, "Phosphate enhances Fgf23 expression through reactive oxygen species in UMR-106 cells," Journal of Bone and Mineral Metabolism, vol. 34, no. 2, pp. 132-139, 2016.Hori M, Kinoshita Y, Taguchi M, Fukumoto S. Phosphate enhances Fgf23 expression through reactive oxygen species in ...
第一步是检查血清磷酸盐水平降低是否是由于肾小管对磷酸盐的重吸收(TRP/ tubular reabsorption of phosphate)减少所致。 排除甲状旁腺激素(PTH)驱动的肾小管磷酸盐重吸收减少后,应检查肾性磷酸盐消耗的其他两个主要原因:固有肾磷酸盐...
Fukumoto S . FGF23-related hypophosphatemic rickets/osteomalacia: diagnosis and new treatment[J]. Journal of Molecular Endocrinology. 2020, 66(2). 版 权 声 明 版权属罕见病新进展所有,欢迎个人转发分享,其他任何媒体、网站如需转载或引用本...
www.boneresearch.org FGF23 and Phosphate Wasting Disorders Xianglan Huang, Yan Jiang, Weibo Xia* Department of Endocrinology, Key Laboratory of Endocrinology, Ministry of Health, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan No. 1, Wangfujing, Dongcheng ...
A decade ago, only two hormones, parathyroid hormone and 1,25(OH)2D, were widely recognized to directly affect phosphate homeostasis. Since the discovery of fibroblast growth factor 23 (FGF23) in 2000 (1), our understanding of the mechanisms of phosphate homeostasis and of bone mineralization ...
肾性磷酸盐消耗综合征(Renal phosphate wasting syndromes)由一组异质性疾病组成,具有多种病因,在生化上表现为低磷酸盐血症。低磷血症的鉴别诊断有很多: 第一步是检查血清磷酸盐水平降低是否是由于肾小管对磷酸盐的重吸收(TRP/ tubular reabsorption of phosphate)减少所致。
and invasion. FGF-23 regulates homeostasis of phosphate and vitamin-D metabolism. FGF-23 inhibits renal tubular phosphate transport by reducing SLC34A1 levels, and negatively regulates osteoblast differentiation and matrix mineralization. FGF-23 also upregulates EGR1 expression in the presence of KL, ...
FGF23 (Fibroblast Growth Factor 23), a well-known marker for phosphate metabolism, has achieved independent significance in the cardiovascular system [1]. Several large-scale prospective studies have established FGF23 as an independent risk marker for heart failure and mortality [2,3]. There is ...