(1) develop better treatments or prevention strategies for AD, or, as a strategy to identify subpopulations at risk for developing AD, or (2) resolve clinically difficult differential diagnoses (e.g., frontotemporal dementia (FTD) versus AD) where the use of PET Aβimaging appears to improv...
PETDementiaGeneAlzheimer’sdiseaseDementias are the most common neurodegenerative diseases and they are increasingly becoming a major public health problem. The most common form of dementia, affecting over 20 million people worldwide, is Alzheimer's disease (AD). AD is a neurodegenerative disease of ...
In a direct comparison, FDG-PET proved superior to MRI with arterial spin labelling (ASL) for diagnosing and differentiating various forms of dementia; however, there remains a need for the latter modality, according to a Belgian study published in the European Journal of Nuclear Medicine and Mol...
With the development of newer technologies, including genetic screening technologies and PET/MRI scanning, the role of genetic studies and neuroimaging is being redefined; indeed, these approaches are able to provide support not only in the clinical diagnosis of dementia, but also in its ...
18F-FDG PET scan patterns for focal-onset dementias using Neurostat 3D-SSP where Lat lateral, LBD Lewy body dementia, Lt left, Med medial, Rt right. Full size image Limitations Non-English studies were excluded from the comprehensive literature review, which may introduce language bias and poten...
Thus, our aim was to create a new [ 18 F]-FDG PET aging and dementia-specific template for spatial normalization, based on images derived from both age-matched controls and patients. We hypothesized that this template would increase spatial normalization accuracy and thereby preserve crucial ...
According to current guidelines from 2005 (CBO) functional brain imaging by PET-scan of the brain has no place in the analysis of a syndrome. Differential diagnosis between and other causes of remains important because there are differences in natural course and treatment. Here we present three ...
本研究中42例特发性PD分别于不同就诊时间接受18F-FDG PET扫描,共57个数据点纳入纵向分析:7例在基线就诊时行第一次扫描,15例在12个月就诊时行第一次扫描,15例在24个月就诊时行第一次扫描,12例在36个月就诊时行第一次扫描,8例...
While FDG-PET may not be a perfect diagnostic tool, the study confirms that currently it is the best available method for monitoring symptoms of dementia, according to Alavi. “Right now, FDG is king when it comes to looking at brain function, not only in Alzheimer’s disease, but also ...
IDLR模型在18F-FDG PET图像中具备对IPD和非典型性帕金森综合征的鉴别诊断潜力。 原发性帕金森病(primary Parkinson's disease,IPD)是常见的神经退行性疾病之一[1],其临床表现与非典型性帕金森综合征(atypical Parkinson's syndrome,APS)如...