(1) develop better treatments or prevention strategies for AD, or, as a strategy to identify subpopulations at risk for developing AD, or (2) resolve clinically difficult differential diagnoses (e.g., frontotemporal dementia (FTD) versus AD) where the use of PET Aβimaging appears to improv...
本研究使用示踪剂注射后10 min的18F-FDG图像,在ROI和体素水平处理和分析下载的18F-FDG PET图像。 本研究中42例特发性PD分别于不同就诊时间接受18F-FDG PET扫描,共57个数据点纳入纵向分析:7例在基线就诊时行第一次扫描,15例在12个...
Dementias are the most common neurodegenerative diseases and they are increasingly becoming a major public health problem. The most common form of dementia, affecting over 20 million people worldwide, is Alzheimer’s disease (AD). AD is a neurodegenerative disease of the central nervous system mainl...
但数据量样本较小且流程较烦琐;Matthews等[22]使用多种机器学习分类器的方法基于FDG PET图像寻找帕金森病的影像标志物,但由于机器学习缺乏可解释性,辅助临床医师判断的说服力不足。
However, the FDG PET scan demonstrated the presence of mild parietal and inferior frontal hypometabolism (arrows indicate the hypometabolism) Clin Transl Imaging (2013) 1:235–246 dementia [65]. In particular, the hypometabolism usually found in parietotemporal and temporal regions in MCI patients ...
Efficient pharmacologic treatment of dementia needs not only to distinguish underlying causes of dementia but also to be installed as soon as possible. Therefore, differential diagnosis and early diagnosis of dementia are utmost importance. F-18 FDG PET is useful for clarifying dementing diseases and ...
With the development of newer technologies, including genetic screening technologies and PET/MRI scanning, the role of genetic studies and neuroimaging is being redefined; indeed, these approaches are able to provide support not only in the clinical diagnosis of dementia, but also in its ...
目的探索自身免疫性脑炎(autoimmune encephalitis, AE)患者 18F-氟代脱氧葡萄糖(fludeoxyglucose, FDG)正电子发射/磁共振计算机断层显像(positron emission tomography/magnetic resonance, PET/MR)表现,寻找提高疾病诊断效能的影像学标记物。 材料与方法回顾性分析25例AE患者(AE组)和11例健康对照(healthy controls, HC...
PET scan results were described by method of measuring FDG-PET avidity, the levels of risk or avidity, and the standardized uptake value threshold used to differentiate benign and cancerous diagnosis of disease. Details of study selection, data extraction, and synthesis are described in the e...
目的探讨幕上肿瘤所致交叉性小脑失联络(crossed cerebellar diaschisis,CCD)发生机制及 18F-FDG PET/CT显像特点。 方法回顾性分析2017年1月至2021年6月行 18F-FDG PET/CT全身显像的86例幕上占位患者,观察并记录幕上病灶位置、数量、大小、SUVmax值、CT值、与基底节关系、是否伴发水肿等情况及小脑不对称指数(asy...