本研究对早期PD患者进行4年纵向PET成像研究,确定与疾病进展相关的区域,分析不同时期感兴趣区(ROI)代谢活性与平均统一帕金森病评定量表(movement disorder society-sponsored revision of the unified Parkinson's disease rating scale,MDS-UP...
6 有关⏫F-FDG PET/CT代谢显像中:Alzheimer病、多发梗死性痴呆、Wilson病、亨廷顿病、Parkinson病引发的痴呆的表现,描述错误的是:(A)AD的FDG PET影像特点是以双侧顶叶和后颞叶皮质、后扣带回为主的葡萄糖代谢减低,而感觉运动皮层、基底神经节和小脑通常不受累...
autonomic dysfunction, and the integrity of the striatal dopaminergic system in patients with multiple system atrophy, pure autonomic failure, and Parkinson’s disease, studied with PET[J]. Brain, 1990, 113(Pt 5): 153...
RAB32 S71R variant has been linked to autosomal dominant Parkinson's disease.We describe the PET signatures of eight PD patients carrying the RAB32 S71R variant.In the majority of patients, a prevalent parietal hypometabolism was observed.This was similar to previous findings reported in LRRK2-...
ObjectiveTo investigate the value of 18F-FDG PET in the diagnosis and differential diagnosis of Parkinson's disease (PD) and multiple system atrophy with parkinsonism-predominant (MSA-P). MethodsTotal 96 patients with PD and 52 patients with MSA-P from The First Hospital of Jilin University fr...
虽然 18F- 氟代脱氧葡萄糖正电子发射断层扫描(18F-FDG PET)得出的帕金森病相关模式(Parkinson's Disease Related Pattern,PDRP)是公认的帕金森病(Parkinson's Disease,PD)生物标志物,但它在前驱期 PD 进展追踪中的作用尚不明确。本研究旨在通过 18F-FDG PET,对 iRBD 患者进行 8 年随访,探索三个时间点的 PD...
IDLR模型在18F-FDG PET图像中具备对IPD和非典型性帕金森综合征的鉴别诊断潜力。 原发性帕金森病(primary Parkinson's disease,IPD)是常见的神经退行性疾病之一[1],其临床表现与非典型性帕金森综合征(atypical Parkinson's syndrome,APS)如...
在此背景下,本综述是以临床为导向,主要总结了 18F-FDG PET显像在神经退行性帕金森综合征中的应用,包括为临床医师提供 18F-FDG PET显像的临床要求和理论基础、典型的 18F-FDG PET模式及其在帕金森综合征鉴别诊断的价值(包括近期研究的初步分析),并展望 18F-FDG PET显像在帕金森病(Parkinson′s disease, PD)认知损害...
帕金森综合征(Parkinsonism)又称震颤麻痹,是指一系列具有帕金森样病变的疾病总称,包括帕金森病(Parkinson's disease, PD)、帕金森叠加综合征(Parkinson-plus syndromes, PPS)以及其他一系列的继发性帕金森综合征,例如药物性、血管性等。其中,帕金森叠加综合征又以多系统萎缩(Multiple system atrophy, MSA)、皮质基底节变性...
Fig 2 Postoperative statistical parametric mapping of FDG PET/CT in 18 patients with Parkinson’s diseses compared with healthy contrals AModeratedly increased MRGlc in cerebellum and pon.BandC: Moderatedly increased rCMRGlc incorpus striatum.D: Midlly increased rCMRGlc insensorimotor area and pr...