Amondys 45 is priced at parity with Sarepta’s other approved exon-skipping treatments. Patients and physicians can access more information at www.SareptAssist.com or by calling 1-888-727-3782. About Amondys 45 Amondys 45 (casimersen) is an antisense oligonucleotide indicated for the treatment of...
Founded in 1978, Biogen is a leading global biotechnology company that has pioneered multiple breakthrough innovations including a broad portfolio of medicines to treat multiple sclerosis, the first approved treatment for spinal muscular atrophy, and two co-developed treatments to address a defining path...
Pain is among the most widespread chronic health condition confronting society today and our inability to manage chronic pain contributes to the opioid abuse epidemic in America. The immune system is known to contribute to acute and chronic pain, but only limited therapeutic treatments such as non-...
Additionally, in a preclinical design, optimized DNAI1 mRNA reduced immune reactivity and was well-tolerated in patients.2 “PCD is a rare genetic lung disorder that currently has no FDA-approved treatments; therefore, receiving this designation is an important recognition for the PCD patient...
mRNA vaccines, which tend to have a favorable side effect profile compared to traditional cancer treatments. Common side effects are usually mild and include symptoms such as fatigue, fever, and injection site reactions, which are similar to those observed with...
inadequacy or challenging development path of future treatments, or life-threatening nature of the disorder, has prompted the EMA, the FDA and MHRA to designate these conditions as well as the drugs aiming at them as “orphan.” A substantial percentage of drugs approved in the past decade fall...
13.2), biological products, and treatments are under different phases of clinical trials [11,12] against COVID-19 (Table 13.3). Besides therapies, new drugs, new molecules, vaccines, and various medical devices, symptomatic treatments to support immune systems are also under clinical evaluation ...
As the first oral penem approved in the US, Orlynvah offers an excellent alternative treatment option for appropriate patients in the underserved uUTI market. With FDA approval and a clear label, we will renew our efforts to achieve a strategic transaction involving Orlynvah with the go...
Currently, in European guidelines, [pembrolizumab and nivolumab] don’t have high-level recommendations because they’re not approved there, but in the United States, hopefully [these agents] will remain options for patients.” As to the FDA’s accelerated approval, Balar does not think...
Bedaquiline, an FDA-approved drug, effectively inhibited mitochondrial ATP production and metastasis in vivo, by targeting the gamma subunit (ATP5F1C) of the mitochondrial ATP-synthase. Full size image More importantly, ATP depletion induced by Bedaquiline also inhibited the growth of MDA-MB-231 ...