The yellow color seen upon gross inspection of these lesions is associated with lipid deposition (cholesterol esters and free cholesterol) within these intimal cells as well as extracellularly. Fatty streaks are distributed throughout the arterial tree, but display a predilection for arterial curvatures...
Fibroblasts can get out of control as we get older, and the result is scar tissue in our livers, our hearts, well…you get it. The recent study showed that both fatty15 and rapamycin lower the proliferation of fibroblasts in cell systems relevant to heart, liver, and lung health. Stopp...
Otto Warburg and colleagues proposed that malignant cells undergo a metabolic switch from oxidative respiration to aerobic glycolysis1. Regarded as the “Warburg effect”, this phenomenon has been observed throughout a broad spectrum of malignancies2. However, multiple...
As stated above, it is unclear whether the NAGs are produced in CNS or whether other peripheral tissues are also involved in production of these signaling lipids. The wide distribution of the NAGs throughout the body (Bradshaw et al., 2009b), including NAGly, likely implies its involvement ...
Liver fat storage, also called hepatic steatosis, is increasingly common and represents a very frequent diagnosis in the medical field. Excess fat is not without consequences. In fact, hepatic steatosis contributes to the progression toward liver fibrosi
Grossing Fatty Tissue Cassette selection is also important. You can see that I have a picture here highlighting multiple types of cassettes. Importantly, when selecting a cassette, ensure there’s enough space in that cassette for fluid penetration throughout the tissue. If that cassette was ...
Tissue fatty acid (FA) composition is one method used to characterize and infer feeding habits in wild animals. In marine mammals, blubber FA content has been used primarily for this purpose, but the extent to which blubber is representative of dietary FAs and metabolism is still being determine...
The measurement was recorded in pounds (lbs.) to the nearest 0.1 lb. Body composition (relative amounts of fat and lean tissue) was determined using Dual Energy X-ray Absorptiometry (DXA, Hologic Horizon-A, Bedford, MA, USA). Participants were instructed to wear comfortable clothing that did...
they can’t tell whether you have simple fatty liver or MASH. There are some tests that can show whether you have fibrosis by measuring the stiffness of your liver.When liver cells die, they're replaced by scar tissue, which is stiff.The stiffer your liver is, the more scarring it has...
The impact of nutritional modification to increase functional polyunsaturated fatty acids (PUFA), such as n-3 and n-6 fatty acids (FA) or conjugated linoleic acid (CLA), on milk proteome profile during early lactation remains largely unknown. We used an