Acyl-(acyl-carrier-protein) hydrolase (EC 3.1.2.14) releases fatty acids from the end-product of fatty acid synthesis in plastids for the subsequent synthesis of glycerolipids in the cytoplasm. Isoelectric focusing of chloroplast stroma proteins from squash cotyledons suggested that there were at ...
Acyl-CoA hydrolase(s) in rabbit mammary gland which control the chain length of fatty acids synthesised. Knudsen J,Clark S,Dils R. Biochemical and Biophysical Research Communications . 1975Knudsen, J., S. Clark, and R. Dils. 1975. Acyl-CoA hydro- lase(s) in rabbit mammary gland which ...
Fatty Acid Oxidation Heart Mitochondria Fatty Acid Chain Elongation, Malonyl-CoA, Carnitine Palmitoyltransferase, Acylcarnitines, Acyl-CoAs Introduction Fatty acids are the major source for ATP production in the heart. Under normoxic conditions, ∼60–70% of the heart's energy requirement is met by...
Fatty acyl-CoAs can be hydrolyzed via the actions of acyl-CoA thioesterases (ACOTs) to produce a free fatty acid and CoA-SH [159] (Fig.1). Like ACSs, ACOT family members differ in their subcellular localization, including localizing within the cytosol, peroxisomes, endoplasmic reticulum, and...
Background [1-3] Long-chain fatty acid acyl-CoA hydrolase antibodies are a type of polyclonal antibody that can specifically bind to long-chain fatty..
The FFAs production can be further greatly improved by co-overexpressing the acetyl-CoA carboxylase to increase the supply of malonyl-CoA, an important precursor for fatty acid synthesis, and deleting the endogenous acyl-CoA synthetase to block the degradation of FFAs in a single host [15, 36]...
The contents of numerous membrane lipids change upon ageing. However, it is unknown whether and how any of these changes are causally linked to lifespan regulation. Acyl chains contribute to the functional specificity of membrane lipids. In this study, w
Six FATP isoforms have been identified in mammalian cells, which contain a common motif for FA uptake and fatty acyl-CoA synthetase function.Citation57 Of these isoforms, FATP2 and FATP5 are highly expressed in the liver, and are utilized as major FATPs for the normal physiological context....
AMPK-mediated phosphorylation inactivates acyl-CoA carboxylase but activates malonyl-CoA decarboxylase, contributing to decreased synthesis and increased degradation, respectively, of malonyl-CoA, which is a critical precursor for fat accumulation. Acetaldehyde can also suppress the function of the ...
The enzymes proposed to catalyze the reactions of NAG metabolism in panel A are enclosed by the ovals: ACS, acyl-CoA synthetase; ADH, alcohol dehydrogenase; AlDH, aldehyde dehydrogenase; BAAT, bile acid-CoA:amino acid N-acyltransferase; FAAH, fatty acid amide hydrolase; GLYATL2, glycine N-...